Association between estimated glomerular filtration rate (eGFR) and asymmetric dimethylarginine (ADMA) concentrations among the elderly in a rural community: a cross-sectional study

Table 4 Association of eGFR with ADMA concentrations in men and women

Variables	model 1		model 2		model 3
Variables	β (μmol/L)	p value	β (μmol/L)	p value	β (μmol/L)	p value
Men (n = 269)
eGFR (mL/min/1.73m²)	− 0.0020	<.0001	−0.0018	0.001	−0.0015	0.005
Systolic BP (mmHg)			0.0000	0.955	−0.0001	0.746
Diastolic BP (mmHg)			−0.0009	0.292	−0.0004	0.635
Total cholesterol (mg/dL)			−0.0001	0.524	−0.0001	0.539
HDL cholesterol (mg/dL)			0.0005	0.333	0.0005	0.351
Diabetes Mellitus			0.0110	0.461	0.0130	0.393
Current smokers (for non-smokers)			0.0227	0.010	0.0224	0.014
Current drinkers (for non-drinkers)			−0.0090	0.520	−0.0079	0.574
Age (yr)					0.0015	0.210
BSA					−0.0003	0.991
Women (n = 382)
eGFR (mL/min/1.73m²)	−0.0009	0.036	−0.0008	0.052	−0.0010	0.039
Systolic BP (mmHg)			−0.0001	0.691	0.0000	0.894
Diastolic BP (mmHg)			0.0004	0.521	0.0003	0.713
Total cholesterol (mg/dL)			0.0000	0.884	0.0000	0.895
HDL cholesterol (mg/dL)			−0.0005	0.363	−0.0004	0.434
Diabetes Mellitus			−0.0112	0.450	−0.0124	0.409
Current smokers (for non-smokers)			0.0231	0.259	0.0238	0.247
Current drinkers (for non-drinkers)			−0.0444	0.067	−0.0442	0.071
Age (yr)					−0.0005	0.608
BSA					0.0102	0.734

eGFR, estimated glomerular filtration rate; BP, blood pressure; HDL, high-density lipoprotein; BSA, body surface area
Model 1: unadjusted
Model 2: adjusted for blood pressure, total and HDL cholesterol, diabetes mellitus, smoking status, and drinking status
Model 3: adjusted for sex, age, BSA, blood pressure, total and HDL cholesterol, diabetes mellitus, smoking status, and drinking status

ISSN: 1471-2318