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Table 3 Association between eGFR and ADMA concentrations in total participants groups stratified by eGFR level

From: Association between estimated glomerular filtration rate (eGFR) and asymmetric dimethylarginine (ADMA) concentrations among the elderly in a rural community: a cross-sectional study

Variablesmodel 1model 2model 3
β (μmol/L)p valueβ (μmol/L)p valueβ (μmol/L)p value
Total participants
 eGFR (mL/min/1.73m2)−0.0013<.0001−0.00130.000−0.00130.000
 Systolic BP (mmHg)  − 0.00010.766−0.00010.768
 Diastolic BP (mmHg)  −0.00010.872−0.00010.868
 Total cholesterol (mg/dL)  0.00000.8960.00000.802
 HDL cholesterol (mg/dL)  0.00000.9520.00000.997
 Diabetes Mellitus  −0.00170.870−0.00220.839
 Current smokers (for non-smokers)  0.02210.0010.02450.004
 Current drinkers (for non-drinkers)  − 0.02270.055−0.02180.074
 Sex    0.00750.595
 Age (yr)    0.00010.912
 BSA    0.00710.734
eGFR ≥ 60 (n = 477)
 eGFR (mL/min/1.73m2)−0.00170.006− 0.00170.005− 0.00170.008
 Systolic BP (mmHg)  −0.00040.263−0.00030.304
 Diastolic BP (mmHg)  0.00000.979−0.00010.917
 Total cholesterol (mg/dL)  0.00000.8920.00000.952
 HDL cholesterol (mg/dL)  −0.00010.812−0.00010.903
 Diabetes Mellitus  0.00750.5520.00700.584
 Current smokers (for non-smokers)  0.02110.0080.02200.023
 Current drinkers (for non-drinkers)  −0.02570.052−0.02630.057
 Sex    0.00400.808
 Age (yr)    0.00000.959
 BSA    0.01110.646
eGFR < 60 (n = 174)
 eGFR (mL/min/1.73m2)−0.00120.143−0.00120.148−0.00120.164
 Systolic BP (mmHg)  0.00050.2800.00050.319
 Diastolic BP (mmHg)  0.00010.8820.00010.948
 Total cholesterol (mg/dL)  −0.00010.550−0.00020.533
 HDL cholesterol (mg/dL)  0.00020.8010.00020.825
 Diabetes Mellitus  −0.02260.244−0.02190.292
 Current smokers (for non-smokers)  0.01930.1720.02350.205
 Current drinkers (for non-drinkers)  −0.00610.824−0.00520.854
 Sex    0.00930.761
 Age (yr)    −0.00010.943
 BSA    0.00040.992
  1. eGFR, estimated glomerular filtration rate; BP, blood pressure; HDL, high-density lipoprotein; BSA, body surface area
  2. Model 1: unadjusted
  3. Model 2: adjusted for blood pressure, total and HDL cholesterol, diabetes mellitus, smoking status, and drinking status
  4. Model 3: adjusted for sex, age, BSA, blood pressure, total and HDL cholesterol, diabetes mellitus, smoking status, and drinking status