Association between estimated glomerular filtration rate (eGFR) and asymmetric dimethylarginine (ADMA) concentrations among the elderly in a rural community: a cross-sectional study

Choi, Hye Rin; Lee, Seung Won; Jeon, Da-Hye; Hur, Nam Wook; Youm, Yoosik; Kim, Hyeon Chang

doi:10.1186/s12877-019-1388-4

Table 3 Association between eGFR and ADMA concentrations in total participants groups stratified by eGFR level

From: Association between estimated glomerular filtration rate (eGFR) and asymmetric dimethylarginine (ADMA) concentrations among the elderly in a rural community: a cross-sectional study

Variables	model 1		model 2		model 3
Variables	β (μmol/L)	p value	β (μmol/L)	p value	β (μmol/L)	p value
Total participants
eGFR (mL/min/1.73m²)	−0.0013	<.0001	−0.0013	0.000	−0.0013	0.000
Systolic BP (mmHg)			− 0.0001	0.766	−0.0001	0.768
Diastolic BP (mmHg)			−0.0001	0.872	−0.0001	0.868
Total cholesterol (mg/dL)			0.0000	0.896	0.0000	0.802
HDL cholesterol (mg/dL)			0.0000	0.952	0.0000	0.997
Diabetes Mellitus			−0.0017	0.870	−0.0022	0.839
Current smokers (for non-smokers)			0.0221	0.001	0.0245	0.004
Current drinkers (for non-drinkers)			− 0.0227	0.055	−0.0218	0.074
Sex					0.0075	0.595
Age (yr)					0.0001	0.912
BSA					0.0071	0.734
eGFR ≥ 60 (n = 477)
eGFR (mL/min/1.73m²)	−0.0017	0.006	− 0.0017	0.005	− 0.0017	0.008
Systolic BP (mmHg)			−0.0004	0.263	−0.0003	0.304
Diastolic BP (mmHg)			0.0000	0.979	−0.0001	0.917
Total cholesterol (mg/dL)			0.0000	0.892	0.0000	0.952
HDL cholesterol (mg/dL)			−0.0001	0.812	−0.0001	0.903
Diabetes Mellitus			0.0075	0.552	0.0070	0.584
Current smokers (for non-smokers)			0.0211	0.008	0.0220	0.023
Current drinkers (for non-drinkers)			−0.0257	0.052	−0.0263	0.057
Sex					0.0040	0.808
Age (yr)					0.0000	0.959
BSA					0.0111	0.646
eGFR < 60 (n = 174)
eGFR (mL/min/1.73m²)	−0.0012	0.143	−0.0012	0.148	−0.0012	0.164
Systolic BP (mmHg)			0.0005	0.280	0.0005	0.319
Diastolic BP (mmHg)			0.0001	0.882	0.0001	0.948
Total cholesterol (mg/dL)			−0.0001	0.550	−0.0002	0.533
HDL cholesterol (mg/dL)			0.0002	0.801	0.0002	0.825
Diabetes Mellitus			−0.0226	0.244	−0.0219	0.292
Current smokers (for non-smokers)			0.0193	0.172	0.0235	0.205
Current drinkers (for non-drinkers)			−0.0061	0.824	−0.0052	0.854
Sex					0.0093	0.761
Age (yr)					−0.0001	0.943
BSA					0.0004	0.992

eGFR, estimated glomerular filtration rate; BP, blood pressure; HDL, high-density lipoprotein; BSA, body surface area
Model 1: unadjusted
Model 2: adjusted for blood pressure, total and HDL cholesterol, diabetes mellitus, smoking status, and drinking status
Model 3: adjusted for sex, age, BSA, blood pressure, total and HDL cholesterol, diabetes mellitus, smoking status, and drinking status

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ISSN: 1471-2318

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