Table 1 General characteristics of study population in total, men, and women
Variables | Total (n = 651) | Men (n = 269) | Women (n = 382) | p-value | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
Age, yr | 71.6 | ± | 7.5 | 72.2 | ± | 6.8 | 71.1 | ± | 7.9 | 0.061 |
Body mass index, kg/m2 | 24.0 | ± | 3.4 | 23.6 | ± | 3.4 | 24.3 | ± | 3.4 | 0.007 |
Body surface area | 1.3 | ± | 0.3 | 1.4 | ± | 0.3 | 1.1 | ± | 0.2 | < 0.001 |
eGFR, mL/min/1.73m2 | 67.7 | [59.5, 76.2] | 69.4 | [61.0, 77.5] | 65.9 | [57.9, 74.3] | 0.003 | |||
eGFR< 60 | 174 | (26.7) | 58 | (21.6) | 116 | (30.4) | 0.012 | |||
eGFR≥60 | 477 | (73.3) | 211 | (78.4) | 266 | (69.6) | ||||
BUN, mg/dL | 15.8 | [13.1, 19.1] | 16.6 | [13.9, 19.3] | 15.2 | [12.7, 18.7] | 0.001 | |||
Creatinine, mg/dL | 0.95 | [0.85, 1.09] | 1.06 | [0.97, 1.19] | 0.88 | [0.81, 0.98] | < 0.001 | |||
ADMA, μmol/L | 0.674 | ± | 0.111 | 0.677 | ± | 0.109 | 0.671 | ± | 0.112 | 0.542 |
ADMA elevation * | 182 | (28.0) | 80 | (12.3) | 102 | (15.7) | 0.396 | |||
Systolic BP, mmHg | 134.2 | ± | 20.1 | 132.9 | ± | 19.8 | 135.1 | ± | 20.3 | 0.165 |
Diastolic BP, mmHg | 72 | ± | 10.1 | 73.1 | ± | 10.4 | 71.2 | ± | 9.9 | 0.023 |
Pulse pressure, bpm | 62.2 | ± | 16.9 | 59.9 | ± | 15.8 | 63.9 | ± | 17.5 | 0.003 |
Fasting glucose, mg/dL | 90 | [83, 101] | 91 | [83, 106] | 89 | [83, 98] | 0.034 | |||
Fasting insulin, uIU/mL | 7.6 | [5.9, 10.3] | 7.0 | [5.5, 10.4] | 7.9 | [6.2, 10.2] | 0.006 | |||
Total cholesterol, mg/dL | 181.9 | ± | 36 | 172.2 | ± | 34.6 | 188.7 | ± | 35.5 | < 0.001 |
HDL cholesterol, mg/dL | 50.9 | ± | 12.7 | 50.1 | ± | 13.3 | 51.5 | ± | 12.3 | 0.147 |
Triglycerides, mg/dL | 136 | [102, 188] | 129 | [94, 178] | 141 | [105, 193] | 0.029 | |||
Diabetes, % | 150 | (23.0) | 71 | (26.4) | 79 | (20.7) | 0.090 | |||
Hypertension, % | 420 | (64.5) | 163 | (60.6) | 257 | (67.3) | 0.080 | |||
Hyperlipidemia, % | 181 | (27.8) | 75 | (27.9) | 106 | (27.8) | 0.970 | |||
Smoking | ||||||||||
Non-smoker | 456 | (70.0) | 82 | (30.5) | 374 | (97.9) | < 0.001 | |||
Past smoker | 117 | (18.0) | 117 | (43.5) | 0 | (0.0) | ||||
Current smoker | 78 | (12.0) | 70 | (26.0) | 8 | (2.1) | ||||
Drinking | ||||||||||
Non-drinker | 512 | (78.7) | 154 | (57.3) | 358 | (93.7) | < 0.001 | |||
Current drinker | 139 | (21.3) | 115 | (42.7) | 24 | (6.3) | ||||