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Table 2 Results of the cognitive tests in relation to two groups based on eGFR

From: Impaired kidney function is associated with lower cognitive function in the elder general population. Results from the Good Aging in Skåne (GÅS) cohort study

Cognitive testCognitive domainNumber of0020participants by eGFRTest result by eGFRMean difference95% CI of differenceP-value
(2-tailed)
  eGFR < 60 mL/min/1.73 m2eGFR ≥60 mL/min/1.73 m2eGFR < 60 mL/min/1.73 m2eGFR ≥60 mL/min/1.73 m2 LowerUpper 
MMSEGlobal778162425.84 ± 3.0827.34 ± 2.32−1.5− 1.74−1.25< 0.001
Digit span forwardLearning and memory76316165.95 ± 1.746.44 ± 1.86−0.48− 0.63− 0.33< 0.001
Free recallLearning and memory73415955.77 ± 2.307.05 ± 2.35− 1.28− 1.48− 1.07< 0.001
RecognitionLearning and memory711158810.85 ± 3.4911.88 ± 2.81−1.03− 1.32− 0.74< 0.001
Word fluencyLanguage765161110.73 ± 4.5812.51 ± 4.93−1.77−2.18− 1.37< 0.001
Digit cancellationComplex attention711160814.56 ± 4.1717.75 ± 4.01−3.18−3.54−2.83< 0.001
Pattern comparisonComplex attention692159821.33 ± 7.2028.22 ± 7.36−6.9−7.55−6.25< 0.001
TMT B-AExecutive function499133726.00 ± 23.3815.12 ± 14.4110.888.6913.08< 0.001
Digit span backwardsExecutive function76016134.87 ± 1.845.54 ± 1.97− 0.67− 0.83− 0.5< 0.001
Mental rotationsPerceptual-motor68215800.56 ± 0.170.62 ± 0.19− 0.06− 0.07− 0.04< 0.001
Confidence judgementMeta-memory74915940.11 ± 0.080.11 ± 0.08− 0,005− 0.010,0020.185
  1. Results of the cognitive tests in relation to impaired kidney function (eGFR < 60 mL/min/1.73 m2) and normal kidney function (eGFR ≥60 mL/min/1.73 m2)
  2. Some participants did not participate in all of the cognitive tests. Every participant performed at least one of the cognitive tests
  3. Equal variances assumed for free recall, digit cancellation, pattern comparison and confidence judgement
  4. Equal variances not assumed for MMSE, digit span forward, recognition, word fluency, TMT B-A, digit span backwards and mental rotations
  5. Values following ± represent SD
  6. Abbreviations: eGFR estimated glomerular filtration rate, CI Confidence interval, SD Standard deviation