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Table 1 Characteristics of the study sample

From: Impaired kidney function is associated with lower cognitive function in the elder general population. Results from the Good Aging in Skåne (GÅS) cohort study

Variable

  

Groups divided by kidney function

  

p-value

All participants

 

eGFR < 30 mL/min/1.73 m2

eGFR 30- < 45 mL/min/1.73 m2

eGFR 45- < 60 mL/min/1.73 m2

eGFR < 60 mL/min/1.73 m2

eGFR ≥60 mL/min/1.73 m2

  

Number (%)

70 (2.9)

241 (9.9)

483 (19.9)

794 (32.7)

1637 (67.3)

 

2431

Age (years)

83.0 ± 8.5

83.8 ± 6.8

78.9 ± 8.3

80.9 ± 8.2

66.9 ± 7.8

< 0.001

71.4 ± 10.3

Sex no. (%)

     

< 0.001

 

 women

37 (52.9)

156 (64.7)

294 (60.9)

487 (61.3)

837 (51.1)

 

1324 (54.5)

 men

33 (47.1)

85 (35.3)

189 (39.1)

307 (38.7)

800 (48.9)

 

1107 (45.5)

Education no. (%)

     

< 0.001

 

 elementary school not completed

1 (1.4)

8 (3.3)

20 (4.1)

29 (3.7)

41 (2.5)

 

70 (2.9)

 elementary school

41 (58.6)

147 (61.0)

277 (57.3)

465 (58.6)

760 (46.4)

 

1225 (50.4)

 secondary school

17 (24.3)

67 (27.8)

128 (26.5)

212 (26.7)

470 (28.7)

 

682 (28.1)

  > = 1 year extra or university degree

11 (15.7)

19 (7.9)

58 (12.0)

88 (11.1)

366 (22.4)

 

454 (18.7)

Country of origin no. (%)

     

< 0.001

 

 Sweden

65 (92.9)

232 (96.3)

445 (92.1)

742 (93.5)

1441 (88.0)

 

2183 (89.8)

 other than Sweden

5 (7.1)

9 (3.7)

38 (7.9)

52 (6.5)

196 (12.0)

 

248 (10.2)

Living no. (%)

     

0.810

 

 in urban environment

58 (82.9)

210 (87.1)

442 (91.5)

710 (89.4)

1469 (89.7)

 

2179 (89.6)

 in rural environment

12 (17.1)

31 (12.9)

41 (8.5)

84 (10.6)

168 (10.3)

 

252 (10.4)

Cardiovascular risk factors

 Hypertension no. (%)

     

< 0.001

 

 Yes

37 (53.6)

112 (46.9)

189 (39.3)

338 (42.8)

330 (20.2)

 

668 (27.6)

 No

32 (46.4)

127 (53.1)

292 (60.7)

451 (57.2)

1303 (79.8)

 

1754 (72.4)

 Smoking no. (%)

     

< 0.001

 

 Active smoker

7 (10)

13 (5.4)

61 (12.7)

81 (10.2)

341 (20.9)

 

422 (17.4)

 Former smoker

35 (50)

87 (36.1)

168 (34.9)

290 (36.6)

642 (39.3)

 

932 (38.4)

 Never smoked

28 (40)

141 (58.5)

253 (52.5)

422 (53.2)

651 (39.8)

 

1073 (44.2)

 Diabetes type 1 no. (%)

     

0.813

 

 Yes

2 (2.9)

4 (1.7)

1 (0.2)

7 (0.9)

13 (0.8)

 

20 (0.8)

 No

67 (97.1)

236 (98.3)

478 (99.8)

781 (99.1)

1621 (99.2)

 

2402 (99.2)

 Diabetes type 2 no. (%)

     

0.011

 

 Yes

8 (11.4)

20 (8.3)

38 (7.9)

66 (8.3)

92 (5.6)

 

158 (6.5)

 No

62 (88.6)

220 (91.7)

445 (92.1)

727 (91.7)

1544 (94.4)

 

2271 (93.5)

  1. Characteristics of the Good Aging in Skåne study sample in relation to kidney function; severely impaired (eGFR < 30 mL/min/1.73 m2), moderately impaired (eGFR 30- < 45 mL/min/1.73 m2), mildly impaired (eGFR 45- < 60 mL/min/1.73 m2) and normal kidney function (eGFR ≥60 mL/min/1.73 m2)
  2. Distribution of the variables was tested between the groups with eGFR ≥60 and < 60 mL/min/1.73 m2. Pearson Chi-Square test was used for all variables except for age, where Mann-Whitney test was used
  3. Values above represent number of participants. Values within parenteses represent percentage. Values following ± represent SD
  4. Abbreviations: eGFR estimated glomerular filtration rate, SD Standard deviation