A prospective study of hepatic safety of statins used in very elderly patients

BMC Geriatrics

Table 3 Twenty-four patients with hepatic aminotransferase elevation after statin treatment

No.	Age	Sex	Statin	Before treatment		After treatment		Elevation levels	Liver enzyme elevation time	Recovery time
No.	Age	Sex	Statin	ALT	AST	ALT	AST	Elevation levels	Liver enzyme elevation time	Recovery time
1	80 ≃ 85	M	Simvastatin	18	20	69	39	Mild	2 weeks	/
2	80 ≃ 85	M	Fluvastatin	21	19	70	37	Mild	1 month	/
3	80 ≃ 85	M	Simvastatin	16	16	165	143	Moderate	1 month	3 months
4	80 ≃ 85	F	Fluvastatin	14	18	49	51	Mild	1 month	/
5	80 ≃ 85	M	Atorvastatin	22	16	123	121	Moderate	3 months	1 month
6	80 ≃ 85	M	Fluvastatin	13	17	98	83	Mild	2 weeks	/
7	85 ≃ 90	M	Rosuvastatin	18	19	87	40	Mild	2 weeks	/
8	80 ≃ 85	M	Simvastatin	12	15	182	244	Moderate	1 month	1 month
9	≥90	M	Simvastatin	13	18	34	42	Mild	2 weeks	/
10	80 ≃ 85	M	Atorvastatin	27	22	1017	511	Severe	3 months	1 month
11	80 ≃ 85	M	Fluvastatin	10	11	66	71	Mild	2 weeks	/
12	80 ≃ 85	M	Simvastatin	15	16	261	301	Moderate	2 months	2 weeks
13	85 ≃ 90	F	Fluvastatin	23	25	51	49	Mild	3 months	/
14	80 ≃ 85	F	Pravastatin	19	17	107	48	Mild	2 months	/
15	80 ≃ 85	M	Fluvastatin	21	14	125	133	Moderate	2 weeks	1 month
16	80 ≃ 85	F	Simvastatin	34	24	979	696	Severe	6 months	1 month
17	≥90	M	Fluvastatin	15	20	47	54	Mild	1 month	/
18	85 ≃ 90	M	Pravastatin	16	13	70	43	Mild	1 month	/
19	80 ≃ 85	M	Pravastatin	13	14	57	51	Mild	1 month	/
20	80 ≃ 85	M	Atorvastatin	16	15	75	48	Mild	2 months	/
21	80 ≃ 85	M	Atorvastatin	10	13	44	53	Mild	2 weeks	/
22	80 ≃ 85	M	Atorvastatin	24	24	76	80	Mild	1 month	/
23	80 ≃ 85	M	Fluvastatin	26	25	267	222	Moderate	1 month	2 weeks
24	80 ≃ 85	M	Pravastatin	31	23	300	260	Moderate	1 month	1 month

M male, F female, ALT alanine aminotransferase, AST aspartate aminotransferase

ISSN: 1471-2318