Fig. 2

Association between physical functioning and AGEs, sRAGE and AGE/sRAGE for men and women, age-stratified. Age-stratification for men: age < 65 N = 487, age > = 65 N = 480; and women: age < 65 N = 455, age > = 65 N = 357. Ref.: PF = 0 (severe limitations in physical functioning). Model 1: age; Model 2: age, years of education, BMI, alcohol consumption, smoking, diet, diabetes mellitus, creatinine clearance, antihypertensive drugs, lipid lowering drugs. AGE = advanced glycation end products; sRAGE = soluble receptor of advanced glycation end products; PF = physical functioning; CI = confidence interval