Fig. 1

Association between physical functioning and AGEs, sRAGE and AGE/sRAGE for men and women. Ref.: PF = 0 (severe limitations in physical functioning). Model 1: age; Model 2: age, years of education, BMI, alcohol consumption, smoking, diet, diabetes mellitus, creatinine clearance, antihypertensive drugs, lipid lowering drugs. AGEs = advanced glycation end products; sRAGE = soluble receptor of advanced glycation end products; PF = physical functioning; CI = confidence interval