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Table 3 Risk of bias assessment for included studies

From: Melatonin for the prevention of postoperative delirium in older adults: a systematic review and meta-analysis

Author (year); Country

 

Randomized controlled trials

Selection bias

Performance bias

Detection bias

Attrition bias

Reporting bias

Other bias

de Jonghe (2014); The Netherlands [29]

Low

Low

Low

High

Low

Low

Nickkholgh (2011); Germany [32]

Low

Low

High

Low

Unclear

Unclear

Sultan (2010); Egypt [33]

Unclear

Low

Unclear

Unclear

Low

Low

Yamaguchi (2014); Japan [34]

Unclear

Unclear

Unclear

Unclear

Low

Unclear

Observational studies

Bias due to confounding

Bias in selection of participants into the study

Bias in classification of interventions

Bias due to deviations from intended interventions

Bias due to missing data

Bias in measurement of outcomes

Bias in selection of the reported results

Artemiou (2015); Slovakia [30]

Moderate

Low

Low

Low

Low

Moderate

Low

Miyata (2017); Japan [31]

Moderate

No information

Low

Low

Low

Low

Low