Table 2 Difference scores in ALDS questionnaire data
From: A randomized controlled efficacy study of the Medido medication dispenser in Parkinson’s disease
ALDS [0–100] | Medido | Control | Effect M - C | P-value of Difference scores a | Effect Sizeb | ||||
|---|---|---|---|---|---|---|---|---|---|
BL (n = 36) | ΔBL-3 months (n = 24) | ΔBL-6 months (n = 29) | BL (n = 51) | ΔBL-3 months (n = 36) | ΔBL-6 months (n = 45) | Effect (95% CI) | |||
All patients | 70.1 (3.9) | 1.1 (2.6) | 2.5 (3.4) | 78.9 (3.3) | 2.7 (2.1) | −0.4 (2.7) | 2.9 (−11.6;5.7) | 0.285 | |
H&Y ≤ 2.5 | 83.0 (4.5) | 0.8 (2.7) | −3.8 (4.2) | 81.4 (3.5) | 2.6 (2.2) | 2.4 (3.3) | −6.2 (− 4.5;16.9) | 0.390 | 0.43 |
H&Y > 2.5 | 57.3 (6.1) | 1.5 (4.8) | 10.7 (5.3) | 75.3 (5.7) | 2.7 (4.0) | −4.1 (4.3) | 14.7 (−28.5;-0.9) | 0.029 | 0.59 |
Disease duration < 5 | 77.1 (5.4) | −5.8 (2.9) | −2.5 (2.8) | 83.9 (5.3) | 2.5 (2.8) | 1.3 (2.6) | −3.8 (−4.1;11.7) | 0.329 | 0.17 |
Disease duration ≥ 5 | 64.5 (5.5) | 6.9 (3.7) | 7.0 (5.4) | 76.4 (4.2) | 2.7 (2.8) | −1.3 (3.9) | 8.2 (−21.7;5.2) | 0.524 | 0.32 |
Age < 70 | 73.3 (4.4) | −0.6 (2.3) | −0.5 (3.5) | 88.5 (3.5) | 1.2 (1.8) | 0.0 (2.7) | −0.5 (−8.5;9.6) | 0.825 | 0.03 |
Age ≥ 70 | 67.2 (6.1) | 4.1 (5.0) | 4.4 (5.8) | 68.3 (5.4) | 4.0 (4.3) | −0.9 (4.9) | 5.3 (−20.7;10.1) | 0.295 | 0.21 |
No caregiver | 80.9 (5.8) | 4.6 (4.7) | 7.2 (4.1) | 90.1 (4.6) | 1.6 (3.7) | −0.6 (3.3) | 7.8 (−18.7;3.0) | 0.126 | 0.29 |
Caregiver | 65.3 (4.8) | −1.8 (2.7) | 0.4 (4.8) | 72.8 (4.2) | 3.7 (2.3) | −0.3 (3.8) | 0.8 (−13.1;11.5) | 0.335 | 0.06 |