Table 4 Weighted MAI sum-score by MAI items
Primary endpoint: Descriptive results by MAI items | |||||
|---|---|---|---|---|---|
n = 83 | MAI-Sum M ± SD | Mean difference | |||
Nr. | Item | t0 | t1 | t2 | t2- t0 |
1 | Is there an indication for the drug? | 7.2 ± 8.6 | 5.1 ± 5.0 | 5.2 ± 5.5 | −2.0 |
2 | Is the medication effective for the condition? | 1.1 ± 2.2 | 0.4 ± 1.1 | 0.3 ± 1.0 | −0.8 |
3 | Is the dosage correct? | 2.2 ± 3.0 | 1.5 ± 2.1 | 1.1 ± 1.5 | −1.1 |
4 | Are the directions correct? | 3.1 ± 3.5 | 2.9 ± 2.8 | 2.2 ± 2.6 | −0.9 |
5 | Are the directions practical? | 0.5 ± 1.4 | 0.0 ± 0.0 | 0.0 ± 0.2 | −0.4 |
6 | Are there clinically significant drug-drug interactions? | 1.7 ± 2.8 | 2.7 ± 3.6 | 2.7 ± 3.8 | 1.0 |
7 | Are there clinically significant drug-disease/condition interactions? | 0.3 ± 0.7 | 0.2 ± 0.5 | 0.1 ± 0.3 | −0.3 |
8 | Is there unnecessary duplication with other drugs? | 0.4 ± 0.8 | 0.3 ± 1.1 | 0.2 ± 0.6 | −0.2 |
9 | Is the duration of the therapy acceptable? | 2.7 ± 2.9 | 1.9 ± 1.8 | 1.8 ± 1.9 | −0.8 |
10 | Is this drug the least expensive alternative compared to others of equal utility? | 4.1 ± 3.7 | 3.2 ± 2.5 | 2.5 ± 2.0 | −1.6 |