Table 4 Subgroup analyses of all-cause mortality according to the degree of frailty, follow-up time and type of ACS
Subgroup | No. of Studies | Unadjusted RR (95%CI) | I2 | P value of interaction | No. of Studies | Adjusted RR (95%CI) | I2 | P value of interaction |
|---|---|---|---|---|---|---|---|---|
The degree of frailty | ||||||||
 Frailty | 11 | 3.16 (2.44, 4.08) | 36.0% | 0.022 | 7 | 2.65 (1.81, 3.89) | 60.2% | 0.003 |
 Pre-frailty | 4 | 1.86 (1.28, 2.71) | 40.1% | 4 | 1.41 (1.19, 1.66) | 0% | ||
Follow-up time | ||||||||
 During admission/within 1 m | 3 | 3.63 (1.91, 6.90) | 0% | 0.96 | 2 | 3.97 (1.65, 9.57) | 0% |  |
  ≤ 1 year | 7 | 3.44 (2.67, 4.44) | 0% | 3 | 3.80 (2.45, 5.90) | 0% | 0.18 | |
  > 1 year | 2 | 3.06 (1.23, 7.65) | 58.8% | 3 | 2.13 (1.32, 3.44) | 73.3% |  | |
Type of ACS | ||||||||
 STEMI | 2 | 2.13 (1.11, 4.09) | 0% | 0.45 | 2 | 6.51 (2.01, 21.10) | 0% | 0.17 |
 NSTEMI | 4 | 2.88 (1.86, 4.47) | 58.8% | 4 | 2.63 (1.51, 4.60) | 73.5% | ||