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Table 1 Characteristics of included studies on association between frailty and clinical outcomes

From: Prognostic value of frailty in elderly patients with acute coronary syndrome: a systematic review and meta-analysis

Study

Study type

Location

Type of ACS

Frailty measure

Age

Sample Size (n)

No.of Males

Prevalence (frailty,%)

Prevalence (pre-frailty)

Follow-up (mo)

Ekerstad 2011

Prospective

Sweden

NSTEMI

CSHA-CFS

≥ 75

307

257

48.50%

N/A

1

Ekerstad 2014

Prospective

Sweden

NSTEMI

CSHA-CFS

≥ 75

307

257

48.50%

N/A

12

Graham 2013

Prospective

Canada

ACS

EFS

≥ 65

183

123

30.05%

35.50%

12

Sanchis 2014

Prospective

Spain

ACS

Green scores

≥ 65

342

196

48.00%

N/A

Mean 25 (31–72)

Sanchis 2018

Prospective

Spain

ACS

Green scores

≥ 65

342

196

48.00%

N/A

Mean 56.4

Kang 2015

Prospective

China

ACS

CSHA-CFS

≥ 65

352

203

43.20%

N/A

6.3

Sujino 2015

Retrospective

Japan

STEMI

CSHA-CFS

≥ 85

62

36

35.50%

N/A

in-hospital

White 2016

Prospective

Multicentre

UA/NSTEMI

Fried Frailty score

≥ 65

4996

2691

4.70%

23.00%

Mean  17.1 (10.4–24.4)

Alonso 2016 a

Prospective

Spain

type 1 MI

SHARE-FI

≥75

190

115

37.90%

28.40%

1

Alonso 2016 b

Prospective

Spain

type 1 MI

SHARE-FI

≥75

202

121

35.10%

36.60%

in-hospital

Alonso 2017

Prospective

Spain

type 1 MI

SHARE-FI

≥75

234

139

40.20%

28.2%

6

Alonso 2018

Prospective

Spain

type 1 MI

SHARE-FI

≥75

285

171

38.20%

29.80%

12

Kirill 2017

Prospective

Russia

ACS

Computer program of geriatric examination

elderly Senile

633

N/A

35.50%

N/A

12

Blanco 2017

Prospective

France

ACS

EFS

≥ 80

236

N/A

20.8%

28.8%

Mean 15.7

Alegre 2018

Prospective

Spain

NSTEMI

FRAIL scale

≥ 80

532

328

27.30%

38.50%

6

  1. CSHA-CFS Canadian Study of Health and Aging Clinical Frailty Scale; EFS Edmonton Frail Scale; STEMI ST-segment elevation myocardial infarction; NSTEMI, non-ST-segment elevation myocardial infarction; ACS acute coronary syndrome; MI myocardial infarction; UA unstable angina; CSHA-CFS Canadian Study of Health and Aging Clinical Frailty Scale; SHARE-FI Survey of Health, Ageing and Retirement in Europe Frailty Index; N/A not available