Table 2 Quantitative studies assessing treatment burden and the specific instruments or question used

[65]

Asthma

Satisfaction with Inhaled Asthma Treatment Questionnaire

[35]

Bronchiectasis

Quality Of Life -B 3.0 questionnaire

[45]

Cancer (breast)

Quality of life questionnaire

[41]

Cancer (Lung)

Number of encounter days (inpatient or outpatient)

[40]

Cancer (seminoma)

Number of treatment episodes.

[34]

Cancer, congestive heart failure or chronic obstructive pulmonary disease

Willingness to Access life-Sustaining Treatment (WALT) instrument

[44]

Celiac disease

Participants asked to rate 4 domains on a scale of 0–100: difficulty in following treatment, perceived importance of following treatment, disease-specific health and overall health.

[52]

Chronic conditions

Living with Medicines Questionnaire V3 (LMQ-3)

[51]

Chronic conditions

Patient Experience with Treatment and Self-management (PETS)

[57]

Diabetes

[7, 54]

Chronic conditions

Health Care Task Difficulty.

[47]

Chronic conditions

Treatment Burden Questionnaire (13-item)

[48]

HIV

[11]

Chronic conditions

Treatment Burden Questionnaire (7-item)

[46, 49, 59]

Chronic conditions

Adapted Treatment Burden Questionnaire (15-item) to include financial burden question and side effects of medication question

[53]

Chronic conditions

Exercise Therapy Burden Questionnaire (ETBQ)

[50]

Multimorbidity

Multimorbidity Treatment Burden Questionnaire (MTBQ)

[38]

Cystic Fibrosis

As part of the CFQ-R, treatment burden was assessed with 3 questions.

[37]

Diabetes

Diabetes Treatment Burden Questionnaire (DTBQ)

[43]

Lupus nephritis

Likert scale rating of treatment burden.

[56]

Medicare beneficiaries

4 questions about things patients are asked to do to stay healthy or treat health problems.

[36]

Psoriasis

Dermatology Life Quality Index

[42]

Stroke

Polypharmacy used as a measure of treatment burden

[39]

Urinary Incontinence

Patient Satisfaction Questionnaire