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Table 2 Association of patient factors and medical conditions with worsening frailty and function

From: EXamining the knowledge, Attitudes and experiences of Canadian seniors Towards influenza (the EXACT survey)

 

Frailty Scaleb

OARS IADL Scaleb

KATZ ADLb,c

OR (95% CI)

P-value

OR (95% CI)

P-value

OR (95% CI)

P-value

Age

1.05 (1.02, 1.07)

<0.001*

1.06 (1.03, 1.09)

< 0.001*

1.08 (1.01, 1.17)

0.03*

Sexa

1.10 (0.95, 1.26)

0.20

1.07 (0.91, 1.27)

0.39

1.17 (0.74, 1.87)

0.50

Influenza/ILI

2.70 (2.03, 3.60)

<0.001*

1.89 (1.33, 2.68)

<0.001*

2.68 (1.07, 6.73)

0.04*

Asthma

1.33 (0.85, 2.07)

0.21

1.89 (1.19, 2.99)

0.01*

0.54 (0.07, 4.13)

0.55

COPD

1.52 (0.91, 2.55)

0.11

1.57 (0.88, 2.77)

0.12

0.80 (0.10, 6.22)

0.83

Blood disorder

1.20 (0.73, 1.96)

0.47

1.21 (0.70, 2.08)

0.50

2.32 (0.71, 7.55)

0.16

Heart disease

1.18 (0.78, 1.78)

0.44

1.77 (1.16, 2.68)

0.01*

2.93 (1.04, 8.29)

0.04*

Kidney disease

1.12 (0.52, 2.40)

0.77

2.07 (1.06, 4.03)

0.03*

N/A

N/A

Liver disease

3.38 (1.26, 9.08)

0.02*

3.27 (1.09, 9.79)

0.03*

N/A

N/A

Neurological disease

1.95 (1.00, 3.83)

0.05*

3.58 (1.96, 6.56)

<0.001*

2.14 (0.27, 16.75)

0.47

Cancer

1.53 (0.84, 2.77)

0.16

1.27 (0.62, 2.58)

0.51

2.39 (0.52, 10.94)

0.26

Significant trouble with memory

2.33 (1.08, 5.02)

0.03*

4.28 (2.13, 8.58)

<0.001*

10.43 (2.82, 38.63)

<0.001*

  1. This table shows the associations of patient demographics and comorbidities with declines in frailty and function at the end of the influenza season
  2. *p ≤ 0.05, logistic regression models
  3. aData from the respondents who identified themselves as transgender were not included in the model due to the low sample size (n = 2)
  4. bHIV was dropped from the model due to collinearity
  5. cKidney disease and liver disease were dropped from the model due to collinearity