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Table 2 Symptoms associated with studied PHARAO propertiesa identified in the medical records of elderly patients

From: Clinical relevance of alerts from a decision support system, PHARAO, for drug safety assessment in the older adults

Sedation symptoms (n = 86) Orthostatic symptoms (n = 90) Constipation (n = 25) Serotonergic symptoms (n = 63) Anticholinergic symptoms (n = 180)
Fatigue/asthenia (66) Fall (37) Somnolence (5) Depressed level of consciousness (2) Dizziness (59) Fall (37) Syncope (12) Orthostatic hypotension (9) Constipation (25) Hypertension (17) Headache (15) Tremor (12) Nausea (10) Palpitations (8) Paraesthesia (7) Diarrhoea (7) Mood altered (4) Tachycardia (4) Musculoskeletal stiffness (3) Hyperhidrosis (3) Sweating (2) Nightmare (2) Confusional state (1) Delusion (1) Libido decreased (1) Muscle spasms (1) Pyrexia (1) Restlessness (1) Sexual dysfunction (1) Dizziness (41) Fall (23) Constipation (22) Fatigue (20) Headache (19) Anxiety (18) Decreased appetite (16) Urinary retention (13) Gastroesophageal reflux disease (13) Dementia (11) Palpitations (11) Mood altered (9) Dry mouth (8) Confusional state (7) Somnolence (4) Visual impairment (3) Memory impairment (3) Nightmare (3) Flushing (2) Pollakiuria (2) Sexual dysfunction (2) Tachycardia (2) Delusion (1) Depressed level of consciousness (1) Eye irritation (1) Hallucination (1) Irritability (1) Libido decreased (1) Vision blurred (1)
  1. aIn total 444 symptoms found in 210 patients