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Table 4 Adjusted diagnostic characteristics of the CAAD screen components

From: Validity of a novel screen for cognitive impairment and neuropsychiatric symptoms in cardiac rehabilitation

Diagnostic characteristics adjusted Cognition Anxiety Apathy Depression
AUC 0.80 0.81 0.79 0.85
Cut-off low risk POI < 0.02 POI < 0.068 POI < 0.090 POI < 0.035
Sensitivity 93% 95% 94% 94%
Specificity 55% 39% 62% 41%
Cut-off high risk POI > 0.30 POI > 0.76 POI > 0.43 POI > 0.57
Sensitivity 27% 5% 13% 50%
Specificity 97% 99% 97% 99%
Low risk: n (%) 55 (43%) 42 (33%) 69 (55%) 47 (37%)
 SD ≤ 1.5 1 1 1 1
 SD > 1.5 54 41 68 46
 NPV 98% 98% 99% 98%
Moderate risk: n (%) 65 (52%) 83 (65%) 51 (41%) 70 (55%)
 SD ≤ 1.5 10 19 13 8
 SD > 1.5 55 64 38 62
 PPV N/A N/A N/A N/A
High risk: n (%) 7 (6%) 2 (2%) 5 (4%) 10 (8%)
 SD ≤ 1.5 4 1 2 9
 SD > 1.5 3 1 3 1
 PPV 57% 50% 40% 90%