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Table 2 Comparison of demographic data, MMSE, HDS-R, ACE-III total and subscores in very mild (CDR 0.5) and mild (CDR 1) dementia groups (n = 178, standard deviation in parenthesis)

From: Validation of Addenbrooke’s cognitive examination III for detecting mild cognitive impairment and dementia in Japan

  VERY MILD MILD P values
n = 113 n = 65
Sex, men/women 43/70 23/42 n.s.
Age 77.6 (7.7) 80.4 (6.0) *
Education, years 11.8 (2.3) 12.3 (2.5) n.s.
MMSE, 0–30 22.5 (3.0) 20.2 (3.1) ***
HDS-R, 0–30 19.7 (3.3) 16.9 (4.0) ***
ACE-III total score, 0–100 68.7 (10.2) 61.1 (11.8) ***
 Attention and Orientation, 0–18 13.8 (2.4) 11.7 (2.6) ***
 Memory, 0–26 10.1 (4.2) 9.1 (4.3) n.s.
 Fluency, 0–14 8.2 (2.5) 7.1 (3.0) *
 Language, 0–26 22.5 (3.4) 20.5 (4.4) **
 Visuospatial, 0–16 14.1 (2.4) 12.7 (3.3) **
  1. MMSE Mini-mental State Examination, HDS-R, Hasegawa Dementia Scale-revised, ACE-III Addenbrooke’s, Cognitive Examination-III; CDR clinical dementia rating, n.s. not significant
  2. *P < 0.05, **P < 0.01, ***P < 0.001