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Table 1 Comparison of demographic data, MMSE, HDS-R, ACE-III total and subscores in control, MCI, and dementia groups (n = 389, standard deviation in parenthesis)

From: Validation of Addenbrooke’s cognitive examination III for detecting mild cognitive impairment and dementia in Japan

 

CONTROL

MCI

DEMENTIA

D vs. C

D vs. M

M vs. C

 

n = 74

n = 137

n = 178

P values

P values

P values

Sex, men/women

30/44

71/66

66/112

n.s.

*

n.s.

Age

72.1 (7.1)

75.3 (8.3)

78.6 (7.2)

***

***

*

Education, years

12.9 (2.3)

13.0 (2.7)

12.0 (2.4)

*

**

n.s.

MMSE, 0–30

28.5 (1.6)

25.5 (2.4)

21.7 (3.3)

***

***

***

HDS-R, 0–30

27.8 (2.2)

23.5 (3.3)

18.7 (3.8)

***

***

***

ACE-III total score, 0–100

93.5 (3.4)

82.7 (7.2)

66.0 (11.4)

***

***

***

 Attention and Orientation, 0–18

17.3 (1.1)

16.0 (1.8)

13.0 (2.7)

***

***

***

 Memory, 0–26

23.6 (2.2)

16.8 (4.2)

9.8 (4.3)

***

***

***

 Fluency, 0–14

11.4 (1.7)

10.2 (2.3)

7.8 (2.7)

***

***

**

 Language, 0–26

25.6 (0.8)

24.6 (1.7)

21.8 (3.9)

***

***

n.s.

 Visuospatial, 0–16

15.6 (0.7)

15.1 (1.4)

13.6 (2.9)

***

***

n.s.

  1. MMSE Mini-mental State Examination, HDS-R Hasegawa Dementia Scale-revised, ACE-III Addenbrooke’s Cognitive Examination-III, MCI mild cognitive impairment, D dementia, C control, M MCI, n.s. not significant
  2. *P < 0.05, **P < 0.01, ***P < 0.001. Pairwise comparisons were performed using Bonferroni’s test