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Table 2 The prognostic factors of the 38 elderly patients with cryptococcal meningitis

From: The clinical characteristics and therapeutic outcomes of cryptococcal meningitis in elderly patients: a hospital-based study

  Survivors (n = 24) Non-survivors (n = 14) p-value
Gender
 Male 11 5  
 Female 13 9 0.542
Underlying disease
 AIDS 0 1 0.368
 Diabetes mellitus 9 6 0.744
 Liver cirrhosis 1 2 0.542
 Hematologic disorders 4 1 0.633
 Autoimmune disorders 1 2 0.542
 Malignancy 3 3 0.650
 Chronic obstructive pulmonary disease 1 4 0.052
 Adrenal insufficiency 3 4 0.387
 Immunocompromised state 7 10 0.011
Initial presentation
 Headache 11 6 0.859
 Altered consciousness 17 12 0.438
 Fever 11 10 0.126
 Seizure 4 2 1.000
 Visual disturbance 1 0 1.000
 Hearing impairment 0 1 0.368
Cerebrospinal fluid data
White blood cell count (109/L) 0.09 0.09 0.950
 Glucose (mmol/L) 2.77 3.21 0.664
 Protein (g/L) 2.65 2.32 0.835
 Lactate (mmol/L) 5.36 5.34 0.982
 Positive India ink stain 3 6 0.050
 Cryptococcal Ag titer (≥1024) 5 7 0.071
 Positive culture result 16 10 0.711
Serum cryptococcal antigen titer (≥1024) 5 7 0.130
Cryptococcemia 2 7 0.006
Extraneural involvement 3 2 1.000
Image finding
 Basal meningeal enhancement 8 4 1.000
 Pseudocyst/VR space dilatation 10 4 0.365
 Hydrocephalus 9 6 0.823
 Recent cerebral infarction 5 6 0.268
 Cryptococcoma 1 0 1.000
  1. AIDS acquired immunodeficiency syndrome, Ag antigen, VR Virchow-Robin