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Table 3 Quality of evidence of ulcer recurrence

From: Effects of preventive use of compression stockings for elderly with chronic venous insufficiency and swollen legs: a systematic review and meta-analysis

Outcome Illustrative comparative risk Relative effect (95% CI) No of participants (studies) Quality of evidence (GRADE)
Assumed risk Control Corresponding risk Compression stockings
Comparison 1: Class 2 compared to class 1 (European standard)
Ulcer recurrence 12 months 175 per 1000 84 fewer per 1000 (from 21 fewer to 122 fewer) RR 0.52 (0.30, 0.88) 399 [2] Moderate1
Comparison 2: Class 3 compared to class 2 (European standard)
Ulcer recurrence 6 months 143 per 1000 51 fewer per 1000 (from 114 fewer to 147 more) RR 0.64 (0.20, 2.03) 93 [1] Very Low2
Comparison 3: Class 3 (European standard) compared to no stockings
Ulcer recurrence 12 months 543 pr. 1000 310 fewer per 1000 (from 168 fewer to 397 fewer) RR 0.43 (0.27, 0.69) 153 [1] Very Low3
  1. 1Downgraded one level due to high risk of bias, 2Downgraded three levels due to severe impression (very wide confidence intervals, low compliance and few participants) and lack of consistency since it is only one trial, 3Downgraded three levels due to high risk of bias, impression (few participants) and lack of consistency since it is only one trial