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Table 3 Quality of evidence of ulcer recurrence

From: Effects of preventive use of compression stockings for elderly with chronic venous insufficiency and swollen legs: a systematic review and meta-analysis

Outcome

Illustrative comparative risk

Relative

effect

(95% CI)

No of participants

(studies)

Quality of evidence (GRADE)

Assumed risk

Control

Corresponding risk

Compression stockings

Comparison 1: Class 2 compared to class 1 (European standard)

Ulcer recurrence

12 months

175 per 1000

84 fewer per 1000 (from 21 fewer to 122 fewer)

RR 0.52 (0.30, 0.88)

399

[2]

Moderate1

Comparison 2: Class 3 compared to class 2 (European standard)

Ulcer recurrence 6 months

143 per 1000

51 fewer per 1000 (from 114 fewer to 147 more)

RR 0.64 (0.20, 2.03)

93 [1]

Very Low2

Comparison 3: Class 3 (European standard) compared to no stockings

Ulcer recurrence 12 months

543 pr. 1000

310 fewer per 1000 (from 168 fewer to 397 fewer)

RR 0.43 (0.27, 0.69)

153 [1]

Very Low3

  1. 1Downgraded one level due to high risk of bias, 2Downgraded three levels due to severe impression (very wide confidence intervals, low compliance and few participants) and lack of consistency since it is only one trial, 3Downgraded three levels due to high risk of bias, impression (few participants) and lack of consistency since it is only one trial