Table 4 Subjects taking drugs increasing risk of pre-renal impairment of kidney function (nonsteroidal anti-inflammatory drugs + angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers + diuretics)
Drug combinations | Total population (n = 4514) | CC | sMDRD | ||
|---|---|---|---|---|---|
< 60 ml/min (n = 1734) | ≥ 60 ml/min (n = 2780) | < 60 ml/min/1.73m2 (n = 855) | ≥ 60 ml/min/1.73m2 (n = 3659) | ||
ACEI/ARB + diuretic; n (%) | 840 (16.61) | 391 (22.55)* | 449 (16.15) | 278 (32.51)# | 562 (15.36) |
ACEI/ARB + NSAID; n (%) | 225 (4.56) | 86 (4.59) | 139 (5.00) | 50 (5.85) | 175 (4.78) |
Diuretic + NSAID; n (%) | 163 (3.61) | 71 (4.09) | 92 (3.31) | 54 (6.32)# | 109 (2.98) |
ACEI/ARB + diuretic + NSAID; n (%) | 98 (2.17) | 39 (2.25) | 59 (2.11) | 31 (3.63)# | 67 (1.83) |