Table 1 List of drugs chosen for analysis and prescription recommendations in patients with impaired renal function
Name of drug | Recommendations | Reference |
|---|---|---|
Gastrointestinal drugs | ||
Metoclopramide | Avoid < 40 ml/min | 28 |
Famotidine | Reduce dose < 50 ml/min | 27,28 |
Ranitidine | Reduce dose < 50 ml/min | 27,28 |
Antidiabetics | ||
Metformin | Avoid < 60 ml/min | 28 |
Acarbose | Avoid < 25 ml/min | 9 |
Gliclazide | Reduce dose < 50 ml/min | 9 |
Antithrombotic agents | ||
Dabigatran | Avoid < 30 ml/min | 27 |
Rivaroxaban | Reduce dose < 50 ml/min | 27 |
Rivaroxaban | Avoid < 30 ml/min | 27 |
Enoxaparin | Reduce dose < 30 ml/min | 27 |
Cardiovascular drugs | ||
Digoxin | Reduce dose < 50 ml/min | 9 |
Sotalol | Avoid < 40 ml/min | 28 |
Atenolol | Reduce dose < 35 ml/min | 28 |
Amiloride | Avoid < 30 ml/min | 27 |
Spironolactone | Avoid < 30 ml/min | 27 |
Hydrochlorothiazide | Avoid < 30 ml/min | 27 |
Rosuvastatin | Reduce dose < 60 ml/min | 9 |
Fenofibrate | Reduce dose < 60 ml/min | 9 |
Antianalgesics | ||
Tramadol | Reduce dose < 30 ml/min | 27 |
Morphine | Reduce dose < 50 ml/min | 9 |
Oxycodone | Reduce dose < 50 ml/min | 9 |
NSAIDs | Avoid < 50 ml/min | 9 |
Antidepressants | ||
Duloxetine | Avoid < 30 ml/min | 27 |
Bupropion | Reduce dose < 50 ml/min | 9 |
Venlafaxine | Reduce dose < 30 ml/min | 9 |
Anti-epileptic drugs | ||
Gabapentin | Reduce dose < 60 ml/min | 27,28 |
Pregabalin | Reduce dose < 60 ml/min | 27 |
Levetiracetam | Reduce dose < 80 ml/min | 9,27 |
Topiramate | Reduce dose < 70 ml/min | 27 |
Other drugs | ||
Piracetam | Reduce dose < 50 ml/min | 9 |
Risperidone | Reduce dose < 50 ml/min | 9 |
Sulpiride | Reduce dose < 50 ml/min | 9 |
Cetirizine | Reduce dose < 30 ml/min | 28 |
Fexofenadine | Reduce dose < 80 ml/min | 28 |
Tizanidine | Reduce dose < 25 ml/min | 9 |
Colchicine | Reduce dose < 30 ml/min | 27 |
Alendronic acid | Avoid < 35 ml/min | 9 |
Methotrexate | Reduce dose < 50 ml/min | 9 |
Memantine | Reduce dose < 30 ml/min | 9,28 |