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Table 1 List of drugs chosen for analysis and prescription recommendations in patients with impaired renal function

From: Use of renal risk drugs in a nation-wide Polish older adult population: an analysis of PolSenior database

Name of drug Recommendations Reference
Gastrointestinal drugs
 Metoclopramide Avoid < 40 ml/min 28
 Famotidine Reduce dose < 50 ml/min 27,28
 Ranitidine Reduce dose < 50 ml/min 27,28
Antidiabetics
 Metformin Avoid < 60 ml/min 28
 Acarbose Avoid < 25 ml/min 9
 Gliclazide Reduce dose < 50 ml/min 9
Antithrombotic agents
 Dabigatran Avoid < 30 ml/min 27
 Rivaroxaban Reduce dose < 50 ml/min 27
 Rivaroxaban Avoid < 30 ml/min 27
 Enoxaparin Reduce dose < 30 ml/min 27
Cardiovascular drugs
 Digoxin Reduce dose < 50 ml/min 9
 Sotalol Avoid < 40 ml/min 28
 Atenolol Reduce dose < 35 ml/min 28
 Amiloride Avoid < 30 ml/min 27
 Spironolactone Avoid < 30 ml/min 27
 Hydrochlorothiazide Avoid < 30 ml/min 27
 Rosuvastatin Reduce dose < 60 ml/min 9
 Fenofibrate Reduce dose < 60 ml/min 9
Antianalgesics
 Tramadol Reduce dose < 30 ml/min 27
 Morphine Reduce dose < 50 ml/min 9
 Oxycodone Reduce dose < 50 ml/min 9
 NSAIDs Avoid < 50 ml/min 9
Antidepressants
 Duloxetine Avoid < 30 ml/min 27
 Bupropion Reduce dose < 50 ml/min 9
 Venlafaxine Reduce dose < 30 ml/min 9
Anti-epileptic drugs
 Gabapentin Reduce dose < 60 ml/min 27,28
 Pregabalin Reduce dose < 60 ml/min 27
 Levetiracetam Reduce dose < 80 ml/min 9,27
 Topiramate Reduce dose < 70 ml/min 27
Other drugs
 Piracetam Reduce dose < 50 ml/min 9
 Risperidone Reduce dose < 50 ml/min 9
 Sulpiride Reduce dose < 50 ml/min 9
 Cetirizine Reduce dose < 30 ml/min 28
 Fexofenadine Reduce dose < 80 ml/min 28
 Tizanidine Reduce dose < 25 ml/min 9
 Colchicine Reduce dose < 30 ml/min 27
 Alendronic acid Avoid < 35 ml/min 9
 Methotrexate Reduce dose < 50 ml/min 9
 Memantine Reduce dose < 30 ml/min 9,28
  1. NSAIDs Nonsteroidal anti-inflammatory drugs