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Table 2 Drug use in older people living in a nursing home versus those living at home

From: Drug use differs by care level. A cross-sectional comparison between older people living at home or in a nursing home in Oslo, Norway

Drug therapeutic group (ATC-3th level)a Drug use prevalence (%) Relative Risk (RR)
H (n = 48,944) NH (n = 2313) 95% CI p-value
Opioids 22.7 46.3 2.0 (2.0, 2.1) <0.01
Paracetamol 18.2 72.1 4.0 (3.9, 4.1) <0.01
Antiepileptic drugs 4.0 9.5 2.4 (2.1, 2.7) <0.01
Dopaminergic drugs 1.5 3.9 2.7 (2.2, 3.4) <0.01
Antipsychotics 4.0 17.2 4.3 (3.9, 4.8) <0.01
Anxiolytics 16.2 48.4 3.0 (2.9, 3.1) <0.01
Hypnotics/sedatives 28.6 49.2 1.7 (1.7, 1.8) <0.01
Antidepressants 11.2 31.6 2.8 (2.7, 1.8) <0.01
Antidementia drugs 2.0 11.4 5.7 (5.0, 6.5) <0.01
Cardiac glycosides 3.2 5.8 1.8 (1.5, 2.2) <0.01
Cardiac nitrates 7.5 15.4 2.1 (1.9, 2.3) <0.01
Loop diuretics 14.0 31.7 2.3 (2.1, 2.4) <0.01
Other diureticsb 6.6 2.9 0.4 (0.3, 0.6) <0.01
Beta-blockers 29.1 24.8 0.9 (0.8, 0.9) <0.01
Calcium channel blockers 19.6 9.0 0.5 (0.4, 0.5) <0.01
Renin–angiotensin drugs 41.1 18.6 0.5 (0.4, 0.5) <0.01
Statins 35.0 5.7 0.2 (0.1, 0.2) <0.01
Antithrombotic agentsc 47.4 44.0 0.9 (0.9, 1.0) <0.01
Inhalatorsd 17.8 18.3 1.0 (0.9, 1.1) 0.55
Corticosteroids, systemic 10.2 6.6 0.7 (0.6, 0.8) <0.01
Antihistamines, systemic 11.6 8.2 0.7 (0.6, 0.8) <0.01
Vitamin B12 and folic acid 6.5 13.6 2.1 (1.9, 2.4) <0.01
Thyroid therapy 10.9 16.1 1.5 (1.4, 1.6) <0.01
Peptic ulcer drugse 17.2 21.4 1.3 (1.2, 1.4) <0.01
Antidiabeticsf 10.2 11.1 1.1 (1.0, 1.2) 0.15
Drugs for glaucoma 9.3 10.4 1.1 (1.0, 1.3) 0.08
Oestrogens 6.3 4.6 0.7 (0.6, 0.9) <0.01
Benign prostate hypertrophy drugs 6.1 2.3 0.4 (0.3, 0.5) <0.01
Osteoporosis drugs 6.5 2.1 0.3 (0.3, 0.4) <0.01
NSAIDs 20.7 5.5 0.3 (0.2, 0.3) <0.01
  1. H (home population), NH (nursing home population). RR (relative risk with 95% confidence interval and p-value and the population living at home as the reference group)
  2. aDrugs with prevalence rates ≥5% in at least one of the populations, except for dopaminergic drugs
  3. bThe vast majority were thiazides
  4. cMostly anti-platelet agents, such acetylsalicylic acid (36.2% vs. 31.2%) and warfarin (11.5% vs. 9.0%)
  5. dSteroid, adrenergic and anticholinergic inhalators
  6. eThe vast majority were proton pump inhibitors
  7. fOral antidiabetic drugs RR = 2.4(2.0, 2.9) and insulin RR = 0.7(0.6, 0.9)