Skip to main content

Advertisement

Table 2 Overall prescription-related changes following the intervention, and at 1 and 6 months

From: Consensus and evidence-based medication review to optimize and potentially reduce psychotropic drug prescription in institutionalized dementia patients

Drug prescription changes Baseline Postintervention 1 month 6 months
Dose increase, n   25 2 9
Dose decrease, n   34 11 6
Discontinued, n   216 15 43
Newly prescribed drugs, n   38 9 42
Reintroduced drugs, n   0 4 22
Patients 0 PD, n (%) 10 (4.00%) 32 (12.80%) 33 (13.31%) 25 (11.06%)
Patients 1–2 PD, n (%) 122 (48.80%) 151 (60.40%) 144 (58.06%) 134 (59.29%)
Patients 3–4 PD, n (%) 89 (35.60%) 60 (24.00%) 65 (26.21%) 55 (24.34%)
Patients > 4 PD, n (%) 29 (11.60%) 7 (2.80%) 6 (2.42%) 12 (5.31%)
Number psychotropic drugs/patient, mean (SD) 2.71 (1.47) 1.95 (1.24) 1.95 (1.26) 2.06 (1.36)
Difference (95% CI) 0.755 (0.624–0.886)* p = 0.000 0.771 (0.635–0.908)* p = 0.000 0.634 (0.474–0.794)* p = 0.000
  1. Prescription-related changes and percentages of patients receiving psychotropic agents grouped into 4 categories (0, 1–2, 3–4, and > 4 psychotropic drugs) at the different time points. The calculation of percentages in each of the 4 categories was made over the total of patients with dementia in the nursing homes (n = 250). Difference in the mean number of psychotropic drugs prescribed before (baseline) and after the intervention and between baseline and 1 and 6 months are shown.
  2. *Difference in the mean number of psychotropic drugs prescribed before (baseline) and after the intervention and between baseline and 1 and 6 months