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Table 2 Overall prescription-related changes following the intervention, and at 1 and 6 months

From: Consensus and evidence-based medication review to optimize and potentially reduce psychotropic drug prescription in institutionalized dementia patients

Drug prescription changes

Baseline

Postintervention

1 month

6 months

Dose increase, n

 

25

2

9

Dose decrease, n

 

34

11

6

Discontinued, n

 

216

15

43

Newly prescribed drugs, n

 

38

9

42

Reintroduced drugs, n

 

0

4

22

Patients 0 PD, n (%)

10 (4.00%)

32 (12.80%)

33 (13.31%)

25 (11.06%)

Patients 1–2 PD, n (%)

122 (48.80%)

151 (60.40%)

144 (58.06%)

134 (59.29%)

Patients 3–4 PD, n (%)

89 (35.60%)

60 (24.00%)

65 (26.21%)

55 (24.34%)

Patients > 4 PD, n (%)

29 (11.60%)

7 (2.80%)

6 (2.42%)

12 (5.31%)

Number psychotropic drugs/patient, mean (SD)

2.71 (1.47)

1.95 (1.24)

1.95 (1.26)

2.06 (1.36)

Difference (95% CI)

0.755 (0.624–0.886)* p = 0.000

0.771 (0.635–0.908)* p = 0.000

0.634 (0.474–0.794)* p = 0.000

  1. Prescription-related changes and percentages of patients receiving psychotropic agents grouped into 4 categories (0, 1–2, 3–4, and > 4 psychotropic drugs) at the different time points. The calculation of percentages in each of the 4 categories was made over the total of patients with dementia in the nursing homes (n = 250). Difference in the mean number of psychotropic drugs prescribed before (baseline) and after the intervention and between baseline and 1 and 6 months are shown.
  2. *Difference in the mean number of psychotropic drugs prescribed before (baseline) and after the intervention and between baseline and 1 and 6 months