Effect of exercise and nutritional supplementation on health-related quality of life and mood in older adults: the VIVE2 randomized controlled trial

Table 2 Health- related quality of life and depressive symptoms mean change

	Physical activity + placebo	Physical activity + supplementation	p between groups^*
PCS
Baseline	45.1 (8.1) (n = 66)	45.8 (7.6) (n = 73)	0.77
6 months	45.2 (9.1) (n = 60)	45.5 (8.1) (n = 68)
Change from baseline to 6 months	0.04 (−1.9,1.9)	−0.7 (−2.3,0.9)
MCS
Baseline	53.1 (8.8) (n = 66)	50.4 (9.5) (n = 73)	0.14
6 months	56.1 (8.1) (n = 60)	53.1 (9.1) (n = 68)
Change from baseline to 6 months	3 (0.5,5.5)^**	2.3 (−0.1,4.8)
CES-D
Baseline	11.1 (6.6) (n = 67)	12.3 (7.7) (n = 67)	0.48
6 months	8.1 (7.7) (n = 65)	9.7 (7.7) (n = 68)
Change from baseline to 6 months	−2.7 (−4.7,-1.22)^**	− 2.8 (−4.5,-1.17)^**

Health- related quality of life (HRQoL) - physical component summary and mental component summary and the Center for Epidemiological Studies Depression Scale scores at baseline and at 6 months and mean change from baseline to 6 months (means (95% CI))
CI confidence interval, PCS physical component summary, MCS mental component summary, CES-D center for epidemiological studies depression scale
^*The p-value is based on the result from the ANCOVA analysis. Adjusted for baseline value, sex, age and study site.^** Significant change within group (p < 0.05)

ISSN: 1471-2318