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Table 3 Longitudinal associations of serum cystatin C and impaired kidney function with incident geriatric depressive symptoms (n = 669)

From: Serum cystatin C, impaired kidney function, and geriatric depressive symptoms among older people living in a rural area: a population-based study

Serum cystatin C or impaired kidney function

N/n

Hazard ratio (95% confidence interval)

Model 1a

Model 2a

Model 3a

Cystatin C, mg/L

 ≤ 1.00

388/78

1.00 (reference)

1.00 (reference)

1.00 (reference)

 1.01–1.25

175/40

1.11 (0.75–1.65)

1.22 (0.82–1.81)

1.21 (0.81–1.80)

 > 1.25

106/39

2.20 (1.48–3.27)

2.23 (1.48–3.34)

2.16 (1.43–3.27)

 p for linear trend

 

0.001

0.001

0.001

Impaired kidney function

 No

544/122

1.00 (reference)

1.00 (reference)

1.00 (reference)

 Yes

125/35

1.57 (1.06–2.32)

1.57 (1.05–2.34)

1.54 (1.03–2.30)

  1. N/n indicates number of subjects/number of persons with depressive symptoms
  2. Abbreviations: MMSE mini-mental state examination, ADL activities of daily living
  3. aModel 1 was adjusted for age, sex, and education; model 2 was additionally adjusted for alcohol consumption, hypertension, stroke, heart disease, cataract, chronic obstructive pulmonary disease, nephritis, and arthritis; and in model 3, MMSE score and ADL-disability were added to model 2