Skip to main content

Advertisement

Table 3 Longitudinal associations of serum cystatin C and impaired kidney function with incident geriatric depressive symptoms (n = 669)

From: Serum cystatin C, impaired kidney function, and geriatric depressive symptoms among older people living in a rural area: a population-based study

Serum cystatin C or impaired kidney function N/n Hazard ratio (95% confidence interval)
Model 1a Model 2a Model 3a
Cystatin C, mg/L
 ≤ 1.00 388/78 1.00 (reference) 1.00 (reference) 1.00 (reference)
 1.01–1.25 175/40 1.11 (0.75–1.65) 1.22 (0.82–1.81) 1.21 (0.81–1.80)
 > 1.25 106/39 2.20 (1.48–3.27) 2.23 (1.48–3.34) 2.16 (1.43–3.27)
p for linear trend   0.001 0.001 0.001
Impaired kidney function
 No 544/122 1.00 (reference) 1.00 (reference) 1.00 (reference)
 Yes 125/35 1.57 (1.06–2.32) 1.57 (1.05–2.34) 1.54 (1.03–2.30)
  1. N/n indicates number of subjects/number of persons with depressive symptoms
  2. Abbreviations: MMSE mini-mental state examination, ADL activities of daily living
  3. aModel 1 was adjusted for age, sex, and education; model 2 was additionally adjusted for alcohol consumption, hypertension, stroke, heart disease, cataract, chronic obstructive pulmonary disease, nephritis, and arthritis; and in model 3, MMSE score and ADL-disability were added to model 2