|
Serum cystatin C or impaired kidney function
|
N/n
|
Hazard ratio (95% confidence interval)
|
|---|
|
Model 1a
|
Model 2a
|
Model 3a
|
|---|
|
Cystatin C, mg/L
|
|
≤ 1.00
|
388/78
|
1.00 (reference)
|
1.00 (reference)
|
1.00 (reference)
|
|
1.01–1.25
|
175/40
|
1.11 (0.75–1.65)
|
1.22 (0.82–1.81)
|
1.21 (0.81–1.80)
|
|
> 1.25
|
106/39
|
2.20 (1.48–3.27)
|
2.23 (1.48–3.34)
|
2.16 (1.43–3.27)
|
|
p for linear trend
| |
0.001
|
0.001
|
0.001
|
|
Impaired kidney function
|
|
No
|
544/122
|
1.00 (reference)
|
1.00 (reference)
|
1.00 (reference)
|
|
Yes
|
125/35
|
1.57 (1.06–2.32)
|
1.57 (1.05–2.34)
|
1.54 (1.03–2.30)
|
- N/n indicates number of subjects/number of persons with depressive symptoms
- Abbreviations: MMSE mini-mental state examination, ADL activities of daily living
- aModel 1 was adjusted for age, sex, and education; model 2 was additionally adjusted for alcohol consumption, hypertension, stroke, heart disease, cataract, chronic obstructive pulmonary disease, nephritis, and arthritis; and in model 3, MMSE score and ADL-disability were added to model 2
