Table 1 Typical schedule for a patient enrolled in the CLEM protocol: summary of different stages
Baseline | Month 6 | Month 12 | Month 18 | Month 24 | |
|---|---|---|---|---|---|
Consent | ✓ | ||||
Inclusion/non inclusion criteria | ✓ | ||||
Medical history or event | ✓ | ✓ | ✓ | ✓ | ✓ |
Clinical examination | ✓ | ✓ | ✓ | ✓ | ✓ |
CDR | ✓ | ✓ | ✓ | ||
DAD | ✓ | ✓ | ✓ | ✓ | ✓ |
IADL | ✓ | ✓ | ✓ | ✓ | ✓ |
MMSE | ✓ | ✓ | ✓ | ||
Neuropsychological diagnosis testing | ✓ | ||||
ADAS-Cog/BREF | ✓ | ✓ | ✓ | ||
NPI | ✓ | ✓ | ✓ | ✓ | ✓ |
Medication | ✓ | ✓ | ✓ | ✓ | ✓ |
Blood sampling | ✓ | ||||
Neurobiotec Biobank | ✓ | ||||
MRI | ✓ | ||||
SPECT-DaTscan® | ✓ | ||||
Amyloid PET | ✓ | ||||
LP (optional) | ✓ |