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Table 2 Clinical characteristics of Alzheimer’s disease and matched cohorts

From: Retrospective assessment of patient characteristics and healthcare costs prior to a diagnosis of Alzheimer’s disease in an administrative claims database

 

AD (n = 16,494)

Matched Cohort (No AD or Dementia) (n = 49,482)

P value*

Mean [SD]

Median

Mean [SD]

Median

Deyo Charlson Comorbidity Index

3.8 [3.0]

3.0

3.0 [2.9]

2.0

< 0.001

RxRisk-V Score

9.8 [4.0]

10.0

8.3 [3.7]

8.0

< 0.001

Number of Unique Medications Used (Drug Classes)

22.0 [14.0]

20.0

18.2[10.7]

17.0

 

Wellness Visit and Assessments, n (%)

 Annual Medicare Wellness Visit

4832 (29.5)

 

17,132 (35.0)

 

< 0.001

 Cognitive Assessment

435 (2.6)

 

114 (0.2)

 

< 0.001

AD medication use at baseline

10,559 (64.0)

 

884 (1.8)

  
  1. Abbreviations: AD Alzheimer’s disease, MCI Mild Cognitive Impairment, SD Standard deviation
  2. RxRisk-V Score was calculated for those with at least one prescription
  3. *Chi square test used for categorical variables; Wilcoxon rank sum test used for continuous variables; Significance level set at P < 0.05