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Table 2 Clinical characteristics of Alzheimer’s disease and matched cohorts

From: Retrospective assessment of patient characteristics and healthcare costs prior to a diagnosis of Alzheimer’s disease in an administrative claims database

  AD (n = 16,494) Matched Cohort (No AD or Dementia) (n = 49,482) P value*
Mean [SD] Median Mean [SD] Median
Deyo Charlson Comorbidity Index 3.8 [3.0] 3.0 3.0 [2.9] 2.0 < 0.001
RxRisk-V Score 9.8 [4.0] 10.0 8.3 [3.7] 8.0 < 0.001
Number of Unique Medications Used (Drug Classes) 22.0 [14.0] 20.0 18.2[10.7] 17.0  
Wellness Visit and Assessments, n (%)
 Annual Medicare Wellness Visit 4832 (29.5)   17,132 (35.0)   < 0.001
 Cognitive Assessment 435 (2.6)   114 (0.2)   < 0.001
AD medication use at baseline 10,559 (64.0)   884 (1.8)   
  1. Abbreviations: AD Alzheimer’s disease, MCI Mild Cognitive Impairment, SD Standard deviation
  2. RxRisk-V Score was calculated for those with at least one prescription
  3. *Chi square test used for categorical variables; Wilcoxon rank sum test used for continuous variables; Significance level set at P < 0.05