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Table 3 Types of medication changes between baseline and 9 months, intervention vs. control group

From: Impact of a nurse-based intervention on medication outcomes in vulnerable older adults

Types of medication change Intervention N = 622 Mean # of changes (% of total)a Control N = 596 Mean # of changes (% of total)a Adjusted differenceb p value
Medication additions 1.79 (44%) 1.51 (42%) 2% 0.37
Medication discontinuations 1.70 (42%) 1.63 (45%) 3% 0.09
Therapeutic substitutions 0.15 (4%) 0.15 (4%) 0% 0.91
Dose increases 0.18 (5%) 0.19 (6%) 1% 0.39
Dose reductions 0.21 (6%) 0.15 (4%) 2% 0.007
TOTAL NUMBER OF CHANGES 4.04 (100%) 3.62 (100%)
  1. a Results show the mean number of each type of medication change within each group, and the percent of all changes attributable to each type of change
  2. b Difference between intervention and control group in the percent of changes attributable to each type of change. Adjusted for baseline subject characteristics and clustering