Impact of a nurse-based intervention on medication outcomes in vulnerable older adults

BMC Geriatrics

Table 3 Types of medication changes between baseline and 9 months, intervention vs. control group

Types of medication change	Intervention N = 622 Mean # of changes (% of total)^a	Control N = 596 Mean # of changes (% of total)^a	Adjusted difference^b	p value
Medication additions	1.79 (44%)	1.51 (42%)	2%	0.37
Medication discontinuations	1.70 (42%)	1.63 (45%)	3%	0.09
Therapeutic substitutions	0.15 (4%)	0.15 (4%)	0%	0.91
Dose increases	0.18 (5%)	0.19 (6%)	1%	0.39
Dose reductions	0.21 (6%)	0.15 (4%)	2%	0.007
TOTAL NUMBER OF CHANGES	4.04 (100%)	3.62 (100%)	–	–

^a Results show the mean number of each type of medication change within each group, and the percent of all changes attributable to each type of change
^b Difference between intervention and control group in the percent of changes attributable to each type of change. Adjusted for baseline subject characteristics and clustering

ISSN: 1471-2318