Risk factor | MMSE | 15WT immediate recall | 15WT delayed recall | ||||||
---|---|---|---|---|---|---|---|---|---|
≤70 | > 70–80 | > 80 | ≤70 | > 70–80 | > 80 | ≤70 | > 70–80 | > 80 | |
APOE ε4 | 0.72 | −4.24 | −10.17 | −0.65 | −3.85 | −5.32 | 0.18 | −4.15 | −8.52 |
Total cholesterol | −3.37 | −0.10 | 1.26 | −1.08 | − 1.09 | 1.53 | 0.97 | −1.53 | 1.27 |
LDL cholesterol | −5.40* | 0.66 | 1.83* | −0.18 | −1.92* | 1.96* | 0.68 | −2.62 | 1.41 |
HDL cholesterol | 7.35 | −2.17 | −1.07 | − 1.84 | 2.64 | 0.50 | 6.21 | 1.45 | 2.97 |
Homocysteine | 0.39 | −0.40 | −0.92 | − 0.39 | − 0.21 | 0.13 | − 0.76* | −0.08 | 0.13* |
Hypertension | 0.04 | −2.14* | 6.52* | −5.65* | −0.22 | 5.06* | −4.04 | 3.54 | 0.43 |
DM | −0.95 | −0.46 | −9.32 | − 0.11 | −3.49 | −0.29 | −1.68 | −5.44 | 4.90 |
MI | 2.42 | −1.59 | 2.23 | 0.41 | 1.93 | 5.64 | 4.90 | 0.62 | 10.14 |
Stroke | 1.25 | −9.16* | 9.16* | 2.60 | −0.34 | 6.70 | 0.79 | −1.58 | −4.30 |
Depressive symptoms | −0.07 | 0.02 | −0.06 | −0.21 | 0.00 | 0.07 | −0.11* | −0.23 | 0.21* |
CRP | −0.18 | 0.18 | 0.19 | −0.21 | 0.03 | 0.19 | −0.19 | −0.11 | 0.16 |
IL-6 | 0.02* | −0.10* | 1.31* | 0.27 | −0.11 | 0.64 | 0.31 | −0.03 | 0.88 |
ACT | 0.00 | 0.01 | 0.06 | −0.01 | − 0.01 | 0.03 | − 0.01* | −0.04 | 0.03* |
Alcohola: minimalb | 2.82* | −0.26 | 7.93* | 3.19 | −3.09 | −0.31 | 5.91 | −3.03 | 0.25 |
Alcohola: moderatec | 0.78 | −0.95 | 3.48 | 2.85 | −3.51 | 1.42 | 3.19 | −0.47 | −0.69 |
Smoking | −0.30 | −1.05 | −5.15 | −5.84* | 0.53* | −1.13 | −4.52 | −2.88 | −0.61 |
Physical activity | 0.00 | 0.00 | 0.02 | −0.01 | 0.01 | 0.00 | 0.01 | 0.01 | 0.00 |