Table 3 PREVENT Neuropsychological Battery

Attention

Trail Making A [52]

Measure of attention, speed and mental flexibility through connecting numbers from 1 to 25 in ascending order.

Processing Speed

Digit Symbol Coding Test (WAIS-IV) [53]

Assessment consisting of 9 digit-symbol pairs followed by a list of digits. Subject instructed to fill in the corresponding symbol within 120 s.

Verbal Memory

WHO/UCLA’s Auditory Verbal Learning Test [54]

Measure of verbal learning and memory. Subject asked to repeat a list of words (List A) for 5 consecutive trials. An interference trial is introduced (List B) followed by immediate recall and a 25-min delayed recall.

Visual Memory

Brief Visuospatial Memory Test – Revised (BVMT) [55]

Measure of visual learning and memory. Target figures presented to subject for 10 s for 3 consecutive drawing trials. After a 25-min delay subject is asked to redraw target figures. Recognition trial is almost administered using 6 novel and 6 target figures.

Executive Function

Stroop Color Word Test [56]

Measure of executive function to assess cognitive control. Subjects instructed to read colors out loud while ignoring the printed words in 45-s.

Trail Making B [52]

Measure of mental flexibility. Subject asked to connect alternating numbers (1–13) and letters (A-L).

Clox-1: Executive Clock Drawing [57]

Measure of visual spatial construction and executive abilities; also screens for dementia. The subject is instructed to draw a clock with hands and numbers and a specific time.

Working Memory

Digit Span Forward [58]

Test of working memory. Subject is asked to repeat back a list of numbers verbatim as they increase in difficulty.

Digit Span Backwards [58]

Test of working memory. Subject is asked to repeat the list of words in backwards order as they increase in difficulty.

Language

Boston Naming Test (Short form) [59]

Assessment of visual naming ability. Subject is asked to name 15 objects after being presented with an illustration.

Complex Ideation Material [60]

Assessment of error detection that may be attributed to dementia. Subject is asked yes/no questions about areas that are considered general knowledge. Subject is then read two stories and asked yes/no questions post-comprehension.

Premorbid Intelligence

North American Adult Reading Test (NAART) [61]

Measure of premorbid intelligence. The subject is asked to read a list of 61 words out loud.

Mood

Center for Epidemiological Studies - Depression Scale (CES-D) [62]

Self-reported questionnaire. The subject is asked to fill out a questionnaire that pertains to their mood and well-being.

Cognitive Screening Tests

Montreal Cognitive Assessment (MoCA) [63]

Assessment of multiple cognitive domains; sensitive to mild cognitive impairment and dementia.

Addenbrooke’s Cognitive Assessment – Revised (ACE-R) [64]

Assessment of multiple cognitive domains; sensitive to MCI and dementia. The test has a built in mini mental state examination (MMSE).