Skip to main content

Table 3 Associations between the factors influencing patient HRQoL and the 13 items of the QoL-AD

From: Factors associated with quality of life in patients with Alzheimer’s disease

  Patient Caregiver
  Depression Polypharmacy Anxiety (NPI) Depression Polypharmacy Caregiver burden
Physical health   *   * *  
Energy     *   *
Mood *   * * * *
Living situation       
Memory *   *    *
Family       *
Marriage       *
Friends       *
Self as a whole    * *   
Ability to do chores       *
Ability to do things for fun *    * * *
Financial situation       
Life as a whole *    *   *
  1. *p < 0.05 (Cochrane Armitage test for trend). For all significant tests, a decrease in the rate of the associated factor (depression, polypharmacy, anxiety or caregiver burden) was observed across the spectrum of responses of the QoL-AD (i.e. from response 1 (poor HRQoL) to item response 4 (excellent HRQoL))
  2. For example, for the item “mood” of the patient QoL-AD, the proportion of patients with depression was 67% for response “1”, 29% for response “2”, 10% for response “3” and 0% for response “4” (p = 0.0002)
  3. Polypharmacy: > 3 medications per day;
  4. NPI NeuroPsychiatric Inventory