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Table 1 General materials of 394 cases (mean ± sd)

From: Informant questionnaire on cognitive decline in the elderly (IQCODE) for assessing the severity of dementia in patients with Alzheimer’s disease

items

Mild dementia

(n = 107)

Moderate dementia

(n = 194)

Severe dementia

(n = 93)

F (P)

Age in years

70.10 ± 9.22

70.57 ± 10.05

68.72 ± 9.77

1.137(0.322)

sex (male:female)

52:55

90:104

42:51

0.124(0.883)

Educationg level

6.21 ± 1.70

5.60 ± 1.87

5.39 ± 1.99

5.506(0.004)

MMSE

19.62 ± 2.04

14.86 ± 2.96

8.29 ± 3.25

402.806(0.000)

DRS

112.75 ± 15.25

88.80 ± 13.16

67.52 ± 15.86

236.362(0.000)

ADAS-cog

29.10 ± 11.08

40.45 ± 12.17

53.27 ± 9.38

89.686(0.000)

  1. Education level: 1.Illiteracy, 2. Old-style private school or family education, 3.Adult literacy class or night school, 4. Primary school drop-outs, 5.Primary school, 6.junior high school, 7.senior high school, 8.College or above
  2. Abbreviations: MMSE the mini-mental state examination, DRS the Mattis dementia rating scale, ADAS-cog the Alzheimer’s disease assessment scale-cognitive subscale