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Table 4 Linear regression models, immune markers associated with the Hamilton rating scale of depression

From: Exploration of 27 plasma immune markers: a cross-sectional comparison of 64 old psychiatric inpatients having unipolar major depression and 18 non-depressed old persons

 

Bivariate linear reg. Models

Linear regression model assessing five immune markers simultaneously with HRSD-17

 

Unadjusted

Adjusteda

Immune markers

Reg. coef. (SE)

p-value

Reg. coef. (SE)

p-value

Reg. coef. (SE)

p-value

IL-1β.b

7.2 (1.1)

< 0.001

3.1 (2.2)

0.157

3.7 (2.2)

0.101

IL-7.b

3.2 (0.5)

< 0.001

1.7 (0.7)

0.017

1.5 (0.7)

0.059

MCP-1.b

8.9 (1.9)

< 0.001

2.4 (1.9)

0.212

3.0 (2.0)

0.146

TNF.b

2.6 (0.7)

< 0.001

−2.5 (1.0)

0.015

−2.5 (1.0)

0.017

VEGF.b

1.8 (0.2)

< 0.001

1.2 (0.4)

0.002

1.1 (0.4)

0.005

  1. Abbreviations: HRSD-17 Hamilton rating scale of depression, CIRS-G cumulative illness rating scale for geriatric patients, BMI body mass index, Reg regression, coef coefficient, SE standard error, IL interleukin, MCP-1 monocyte chemotactic protein, TNF tumour necrosis factor, VEGF vascular endothelial growth factor
  2. aAdjusted for age, gender, CIRS-G (continuous) and BMI
  3. bLN transformed.