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Table 4 Results of generalized linear regression model of patient EQ-5D proxy index values as a function of LTCI & covariates (n = 300)

From: Alzheimer’s disease severity and its association with patient and caregiver quality of life in Japan: results of a community-based survey

Characteristic Reference Category Variables B 95% LCL 95% UCL P-Value
(Intercept) 0.761 0.629 0.894 < 0.001
Patient characteristics
AD dementia severity Low severity High severity −0.340 − 0.414 − 0.267 < 0.001
Medium severity − 0.072 − 0.134 − 0.01 0.022
Sex Female Male −0.030 − 0.078 0.018 0.220
Age < 80 years 90+ years 0.001 − 0.067 0.069 0.974
80–89 years 0.010 −0.045 0.064 0.728
Caregiver characteristics
Sex Female Male −0.041 − 0.085 0.002 0.064
Age X employment status 18–49 years and unemployed 65+ years and unemployed 0.026 −0.096 0.149 0.677
50–64 years and unemployed − 0.106 −0.202 − 0.009 0.032
Unemployed and 18–49 years Employed and 18–49 years − 0.076 − 0.167 0.014 0.098
65+ vs. 18–49 years and unemployed 65+ vs. 18–49 years and employed 0.026 −0.139 0.19 0.758
50–64 vs. 18–49 years and unemployed 50–64 vs. 18–49 years and employed 0.144 0.038 0.249 0.008
% average daily care for which caregiver is responsible 0.000 0.000 0.001 0.378
% average daily care from visiting nurse/home-helper −0.002 −0.003 0.000 0.008
Total average hours of care required per day −0.042 −0.061 − 0.024 < 0.001
Years providing care for AD dementia patient < 2 years 2 to < 4 years 0.022 − 0.061 0.105 0.603
4 to < 6 years 0.050 −0.037 0.137 0.258
6+ years 0.025 −0.062 0.112 0.575
Can’t recall 0.084 −0.018 0.186 0.108
Marital status Single Married / living with partner 0.011 −0.037 0.059 0.660
Divorced / separated / widowed −0.068 −0.145 0.01 0.087
Relationship with patient In-law, extended, not related Offspring of patient (caregiver ≤20 years) 0.021 −0.031 0.074 0.420
Spouse / sibling / parent of patient (caregiver > 20 years) −0.048 −0.166 0.07 0.424
(Scale) 0.028 0.024 0.033  
  1. Note. Presented are normal generalized linear model results. AD Alzheimer’s disease, B unstandardized beta, LCL lower confidence limit, UCL upper confidence limit
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