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Table 1 Clinical and demographic characteristics at baseline

From: Association between vascular comorbidity and progression of Alzheimer’s disease: a two-year observational study in Norwegian memory clinics

  Total   
Age, years, mean (SD) 282 73.3 (8.8)
Female, n (%) 282 153 (54.3)
Education, years, mean (SD) 282 11.7 (3.6)
Drugs in regular use, mean (SD) 280 3.1 (2.6)
 Antihypertensives, number of users (%) 280 137 (48.9)
 Statins, number of users (%) 280 85 (14.7)
 Antidiabetic agents (number of users, %) 280 20 (7.1)
 Antithrombotic agents (number of users, %) 280 131 (46.8)
  Platelet inhibitors (number of users, %) 280 114 (40.4)
  Anticoagulants (number of users, %) 280 21 (7.5)
ApoE ε4 carrier, n (%) 252 154 (61.1)
MMSE (0–30), mean (SD) 280 23.7 (4.4)
CDR sum of boxes (0–18), mean (SD) 282 4.2 (2.8)
Vascular risk factors (VRFs)
 Hypertension, n (%) 282 234 (83.0)
 Hypercholesterolemia, n (%) 282 149 (52.8)
 Diabetes mellitus, n (%) 282 26 (9.2)
 Overweight (BMI > 25), n (%) 256 106 (41.4)
 Smoking (current), n (%) 275 26 (9.5)
Framingham Stroke Risk Profileb (0–1), women, mean (SD) 113 0.21 (0.14)
Framingham Stroke Risk Profileb (0–1), men, mean (SD) 92 0.26 (0.16)
Vascular diseases
 Atrial fibrillation, n (%) 282 28 (9.9)
 History of cerebrovascular event (stroke or TIA), n (%) 282 43 (15.2)
 History of heart disease, n (%) 282 46 (16.3)
 Left ventricular hypertrophy in ECGa, n (%) 211 8 (3.8)
 History of peripheral vascular disease, n (%) 273 7 (2.6)
 Estimated GFR < 60 ml/min/1.73m2, n (%) 273 47 (17.2)
MRI findings
Medial temporal lobe atrophy (mean of both sides), mean (SD) 203 1.9 (0.9)
Cortical infarcts, n (%) 206 9 (4.4)
Lacunar infarcts, n (%) 206 33 (16.0)
White matter hyperintensities
 Fazekas 0 or 1, n (%) 205 84 (40.9)
 Fazekas 2, n (%) 205 53 (25.9)
 Fazekas 3, n (%) 205 68 (33.2)
Cerebrovascular disease: cortical infarcts, lacunes or Fazekas ≥2, n 206 128 (62.1)
Cerebrovascular disease: cortical infarcts, lacunes or Fazekas 3, n 206 88 (42.7)
  1. aFramingham criteria
  2. bTen year probability of stroke