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Table 4 Cox regression analyses for 1-year all-cause death

From: Predictive biomarkers for death and rehospitalization in comorbid frail elderly heart failure patients

 

1-year all-cause death

 

Univariate

Multivariate

 

HR

95%CI

p-value

HR

95%CI

p-value

Age

1.08

1.05–1.11

< 0.001

1.08

1.05–1.12

< 0.001

Female Sex

1.28

0.89–1.85

0.2

1.73

1.16–2.59

0.008

NYHA

2.01

1.40–2.90

< 0.001

–

–

–

Diabetes

1.03

0.83–1.29

0.8

   

Charlson comorbidity index

1.15

1.05–1.26

0.002

1.17

1.06–1.28

0.001

Barthel index

0.98

0.97–0.99

< 0.001

0.99

0.98–1.00

0.008

Urea

1.01

1.00–1.01

< 0.001

–

–

–

Creatinine

1.00

1.00–1.01

0.4

   

Hb

0.87

0.77–0.97

0.02

–

–

–

Na

0.97

0.93–1.02

0.2

   

NT-proBNPa

1.65

1.37–1.98

< 0.001

–

–

–

ST2a

1.86

1.59–2.18

< 0.001

1.45

1.21–1.74

< 0.001

CA125a

1.58

1.33–1.89

< 0.001

1.35

1.11–1.65

0.003

Hs-TnIa

1.29

1.09–1.52

0.003

–

–

–

  1. aLog-transformed and per 1 SD
  2. CA125 cancer antigen 125, NT-proBNP N-terminal pro-brain natriuretic peptide, hs-TnI high-sensitivity troponin I, ST2 Interleukin-1 receptor-like 1
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BMC Geriatrics

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