Characteristics of elderly patients with polypharmacy who refuse to participate in an in-hospital deprescribing intervention: a retrospective cross-sectional study

Table 2 Prevalence of PIM^a use according to drug subcategory at admission among the 136 included orthopedic patients

	Deprescribing for polypharmacy		P-value^b
	Acceptance	Refusal
	N = 82	N = 54
Number of PIMs, mean ± SD	1.5 ± 1.2	1.6 ± 1.3	0.52
Any PIMs, n (%)	64 (78.0)	41 (75.9)	0.84
Category of PIMs, n (%)
Benzodiazepines	30 (36.6)	18 (33.3)	0.72
Proton pump inhibitors	26 (31.7)	19 (35.2)	0.71
NSAIDs	7 (8.5)	7 (13.0)	0.41
Hypnotics	8 (9.8)	5 (9.3)	1.00
Anticholinergics	3 (3.7)	6 (11.1)	0.16
Anticonvulsive drugs	4 (4.9)	5 (9.3)	0.48
Antipsychotics	7 (8.5)	1 (1.9)	0.15
Opioids	2 (2.4)	5 (9.3)	0.11
Antidepressants	3 (3.7)	4 (7.4)	0.43
Ticlopidine or dipyridamole	5 (6.1)	1 (1.9)	0.40
Peripheral alpha-1 blocker	2 (2.4)	4 (7.4)	0.22

^aPIMs were defined based on the 2015 American Geriatric Society Beers Criteria
^bFisher’s exact tests or Student’s t-tests were used for comparisons between the acceptance and refusal groups. The threshold for statistical significance was set at p < 0.05

ISSN: 1471-2318