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Table 2 Psychotropic medication

From: Psychotropic and anti-dementia treatment in elderly persons with clinical signs of dementia with Lewy bodies: a cross-sectional study in 40 nursing homes in Sweden

  ATCa Study populationb
N (%)
Dementia diagnosesc P-value Clinical signsdof DLB P-value Age groupse P-value
Yes
N (%)
No
N (%)
  0–1
N (%)
2–4
N (%)
  ≤85 years
N (%)
≥86 years
N (%)
 
Antipsychotics
Any N05A 132 (21.6) 102 (23.2) 29 (18.8)   93 (19.1) 39 (31.5) * 71 (27.4) 61 (17.4) **
Haloperidol   42 (7.1) 28 (6.6) 14 (9.3)   25 (5.3) 17 (14.3) ** 23 (9.3) 19 (5.5)  
Risperidone   57 (9.6) 49 (11.5) 8 (5.3)   45 (9.5) 12 (10.1)   29 (11.7) 28 (8.1)  
Other f   11 (1.9) 9 (2.1) 2 (1.3)   7 (1.5) 4 (3.4)   6 (2.4) 5 (1.5)  
Anxiolytics
Any N05B 336 (58.4) 263 (61.7) 73 (49.0) * 251 (54.8) 85 (72.6) *** 136 (56.2) 200 (60.1)  
Oxazepam   308 (53.6) 248 (58.2) 60 (40.3) ** 228 (49.8) 80 (68.4) *** 125 (51.7) 183 (55.0)  
Diazepam   44 (7.7) 31 (7.3) 13 (8.7)   25 (5.5) 19 (16.2) *** 22 (9.1) 22 (6.6)  
Hypnotics/sedatives
Any N05C 234 (40.7) 176 (41.3) 58 (38.9)   186 (40.6) 48 (41.0)   103 (42.6) 131 (39.3)  
Zopiclone   189 (32.9) 139 (32.6) 50 (33.6)   145 (31.7) 44 (37.6)   78 (32.2) 111 (33.3)  
Other g   77 (13.4) 67 (15.7) 10 (6.7) ** 68 (14.8) 9 (7.7) ** 39 (16.1) 38 (11.1)  
Anti-depressants
Any N06A 290 (50.4) 225 (52.8) 65 (43.6) ** 233 (48.4) 57 (60.6) * 129 (53.3) 161 (48.3)  
SSRI   204 (35.5) 156 (36.6) 48 (32.2)   157 (34.3) 47 (40.2)   88 (36.4) 116 (34.8)  
Mirtazapine   127 (22.1) 103 (24.2) 24 (16.1) * 99 (20.6) 28 (29.8)   58 (24.0) 69 (20.7)  
Venlafaxine   18 (3.1) 14 (3.3) 4 (2.7)   15 (3.1) 3 (3.2)   13 (5.4) 5 (1.5) *
Other   6 (1.0) 4 (0.9) 2 (1.3)   4 (0.9) 2 (1.3)   2 (0.8) 4 (1.2)  
  1. aAnatomical Therapeutic Chemical (ATC) Classification System
  2. bAll participants: 610 (100%), with registered medical lists for 575 (94%) participants
  3. cDementia diagnoses: there were (N = 440) with a dementia diagnosis and (N = 154)participants without a dementia diagnosis
  4. dClinical signs: visual hallucinations, fluctuating cognition, parkinsonism and REM sleep behaviour disorder
  5. eAge group total 610 (100%): ≤85 years (N = 259) and ≥86 years (N = 351)
  6. fOther (N05A): Clozapine (n = 1), Olanzapine (n = 8), Quetiapine (n = 2)
  7. gOther (N05C): Melatonine (n = 21), Klometiazol (n = 58), Nitrazepam (n = 6), Propriomazin (n = 5)
  8. *P-value < 0.05, **P-value< 0.005, ***P-value < 0.001