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Table 3 Outcomes of study

From: Economic evaluation of an extended nutritional intervention in older Australian hospitalized patients: a randomized controlled trial

Outcomesa

 

Control

 

Intervention

Difference (Bootstrapped 95% CI)

n

Mean

n

Mean

 

Base Case Analysis (imputed cases)b

 EQ-5D-5 L and QALY gains

  EQ-5D-5 L at baseline

70

0.6746 (0.0284)

78

0.6934 (0.0276)

0.1088 (−0.0489, 0.0916)

  EQ-5D-5 L at 3 months

70

0.5787 (0.0407)

78

0.6358 (0.0349)

0.0571 (−0.0556,0.1560)

  Unadjusted QALYs

70

0.1578 (0.0064)

78

0.1659 (0.0067)

0.0081 (−0.0090, 0.0265)

  Adjustedc QALYs

    

0.005 (−0.0079, 0.0199)

 PG-SGA Scores

  PG-SGA Scores at baseline

70

13.3286 (0.5817)

78

12.1123 (0.4951)

−1.2163 (− 2.6163,0.1793)

  PG-SGA Scores at 3 months

70

7.3770 (0.4098)

78

5.9136 (0.4054)

−1.4634 (− 2.4801, −0.1896)

  Unadjusted improvement in PG-SGA Scoresd

70

5.9516 (0.6594)

78

6.1987 (0.5547)

0.2471 (−1.4931, 1.8661)

  Adjustedc improvement in PG-SGA Scoresd

    

1.3238 (0.0240, 2.3858)

 Inpatient stay

  LOS in days

69

9.9 (7.2)

71

6.9 (5.3)

3.0 (0.9, 5.1)

Sensitivity analysis (complete cases)e

 EQ-5D-5 L and QALY gains

  EQ-5D-5 L at baseline

69

0.6736 (0.0290)

77

0.6926 (0.0272)

0.0189 (−0.0537, 0.1003)

  EQ-5D-5 L at 3 months

60

0.5672 (0.0487)

69

0.6360 (0.0407)

0.0688 (−0.0553, 0.2043)

  Unadjusted QALYs

59

(0.1553 (0.0076)

69

0.1658 (0.0075)

0.0105 (−0.0096, 0.0291)

  Adjustedc QALYs

    

0.0060 (−0.0086, 0.0216)

 PG-SGA Scores

  PG-SGA Scores at baseline

69

13.3478 (0.5848)

74

12.0946 (0.5240)

−1.2532 (−2.9491, 0.2727)

  PG-SGA Scores at 3 months

46

6.9783 (0.6167)

57

5.8070 (0.5185)

−1.712 (−2.7446, 0.3698)

  Unadjusted improvement in PG-SGA Scoresd

46

6.1739 (0.8876)

57

5.8596 (0.7081)

−0.3143 (− 2.4223, 1.8485)

  Adjustedc improvement in PG-SGA Scoresd

    

0.9849 (−0.5601, 2.5912)

  1. aEQ-5D-5 L EuroQoL 5 Dimensions 5 Levels, QALY Quality Adjusted Life Years, PG-SGA Patient Generated Subjective Global Assessment, LOS Length of Hospital Stay
  2. bMultiply imputed values. Multiple imputations carried out to account for up to 12% of the EQ-5D-5 L utility scores (2 or 1% of baseline and 19 or 1% of 3-month EQ-5D-5 L scores)
  3. cThese scores have been adjusted for baseline differences
  4. dThese PG-SGA scores were reverse scored so that a positive score reflects an improvement in nutrition status
  5. eTrial participants with complete information on baseline and 3-month outcomes