Table 2 Association of total cholesterol with all-cause, cardiovascular, and non-cardiovascular mortality

cholesterol (mmol/l)

No. of subjects

No. of deaths

Mortality rate (per 1000 person-years)

Hazard ratio (95% CI)^a

No. of deaths

Mortality rate (per 1000 person-years)

Hazard ratio (95% CI)^b

No. of deaths

Mortality rate (per 1000 person-years)

Hazard ratio (95% CI)^b

  < 5.18

687

325

71.8

1.00 (Ref.)

205

45.3

1.00 (Ref.)

120

26.5

1.00 (Ref.)

 5.18–6.21

1207

394

43.2

0.71 (0.61–0.83)

236

25.9

0.82 (0.66–1.02)

158

17.3

0.85 (0.66–1.09)

  ≥ 6.22

1196

340

35.6

0.68 (0.57–0.80)

221

23.2

0.98 (0.77–1.23)

119

12.5

0.67 (0.51–0.88)

  P for trend

<0.001^a

0.882^b

0.004^b

  < 5.18

495

259

84.7

1.00 (Ref.)

162

53.0

1.00 (Ref.)

97

31.7

1.00 (Ref.)

 5.18–6.21

1066

358

44.7

0.70 (0.59–0.82)

213

26.6

0.79 (0.63–1.00)

145

18.1

0.88 (0.67–1.16)

  ≥ 6.22

1140

324

35.5

0.65 (0.54–0.77)

209

22.9

0.91 (0.72–1.17)

115

12.6

0.69 (0.51–0.92)

  P for trend

<0.001^a

0.573^b

0.009^b

  < 5.18

189

64

44.0

1.00 (Ref.)

42

28.9

1.00 (Ref.)

22

15.1

1.00 (Ref.)

 5.18–6.21

138

33

29.6

0.76 (0.49–1.19)

22

19.7

0.84 (0.47–1.50)

11

9.9

0.75 (0.35–1.61)

  ≥ 6.22

54

14

33.2

1.03 (0.56–1.90)

11

26.0

1.47 (0.77–2.81)

3

7.1

0.52 (0.14–1.98)

  P for trend

0.961^a

0.561^b

0.244^b