Intervention to improve the appropriate use of polypharmacy for older patients with hip fractures: an observational study

Table 3 Relevant patient outcome results according to study group

Outcome	Intervention n = 32	Usual care n = 132	Odds ratio (95% CI)	p-value
Primary composite outcome
Death or any new fracture, n (%)	7 (21.9)	28 (21.2)	1.04 (0.41–2.65)	1.00
Secondary outcomes
Death, n (%)	4 (12.5)	13 (9.8)	1.31 (0.40–4.32)	0.75
Any new fracture, n (%)	3 (9.4)	15 (11.4)	0.81 (0.22–2.97)	1.00
Cardiovascular event^a, n (%)	0 (0.0)	12 (9.1)	Not applicable	0.13
Unplanned hospital admission, n (%)	7 (21.9)	25 (18.9)	1.20 (0.47–3.08)	0.80
Adverse events during hospital stay
Delirium, n (%)	12 (37.5)	63 (47.7)	0.66 (0.30–1.45)	0.33
In-hospital infection^b, n (%)	6 (18.8)	17 (12.9)	1.56 (0.56–4.34)	0.38
Adverse drug event^c, n (%)	1 (3.1)	18 (13.6)	0.20 (0.03–1.59)	0.30
Cardiovascular event, n (%)	0 (0.0)	7 (5.3)	0.26 (0.01–4.63)	0.36
In-hospital death, n (%)	1 (3.1)	5 (3.8)	0.82 (0.09–7.27)	1.00

^aCardiovascular events included myocardial infarction, heart failure, venous thromboembolism and stroke
^bThis category included any infections that required antibiotic treatment
^cAdverse drug events were included only if the medication was discontinued due to its harmful effect

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