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Table 3 PIP and PIM by STOPP and Beers criteria in elderly taking antidepressants

From: Potentially inappropriate prescriptions for elderly people taking antidepressant: comparative tools

Condition/

Drug

PIM number of patients

PIP in prescriptions

STOPP criteria

n = 69 (%)

n = 463 (%)

Dementia

tricyclic antidepressants

1(1.4)

2 (0.4)

Glaucoma

tricyclic antidepressants

1 (1.4)

5 (1.1)

Cardiac conductive abnormalities

tricyclic antidepressants

5 (7.2)

32 (6.9)

Use of calcium channel blocker

tricyclic antidepressants

3 (4.3)

5 (1.1)

Long-term (> 1 month)

long-acting benzodiazepines and benzodiazepines with long-acting metabolites a

54 (78.3)

397 (85.7)

Long-term (> 1 month)

neuroleptics as long-term hypnotics

15(21.7)

96(20.7)

Beers criteria

n = 60 (%)

n = 403 (%)

Arrhythmias

tricyclic antidepressants

4(6.6)

32(7.9)

Depression

long-term benzodiazepines use

41(68.3)

287(71.2)

Depression

methyldopa

1(1.6)

5 (1.2)

Concomitant use ≥3 CNS-active drugsb

tricyclic antidepressant + SSRI + benzodiazepine + antipsychotic

1 (1.6)

3 (0.7)

tricyclic antidepressant + SSRI + antipsychotic

2(3.3)

4 (1.0)

antidepressant + benzodiazepine + antipsychotic

10 (16.6)

64 (15.9)

antidepressant + benzodiazepine + two antipsychotics

1 (1.6)

8 (1.9)

  1. SSRI selective serotonin reuptake inhibitor
  2. aclonazepam; diazepam;
  3. b CNS drugs = central nervous system active drugs: antipsychotics; benzodiazepines; tricyclic antidepressants; SSRIs;