From: Potentially inappropriate prescriptions for elderly people taking antidepressant: comparative tools
Condition/ | Drug | PIM number of patients | PIP in prescriptions |
---|---|---|---|
STOPP criteria | n = 69 (%) | n = 463 (%) | |
Dementia | tricyclic antidepressants | 1(1.4) | 2 (0.4) |
Glaucoma | tricyclic antidepressants | 1 (1.4) | 5 (1.1) |
Cardiac conductive abnormalities | tricyclic antidepressants | 5 (7.2) | 32 (6.9) |
Use of calcium channel blocker | tricyclic antidepressants | 3 (4.3) | 5 (1.1) |
Long-term (> 1 month) | long-acting benzodiazepines and benzodiazepines with long-acting metabolites a | 54 (78.3) | 397 (85.7) |
Long-term (> 1 month) | neuroleptics as long-term hypnotics | 15(21.7) | 96(20.7) |
Beers criteria | n = 60 (%) | n = 403 (%) | |
Arrhythmias | tricyclic antidepressants | 4(6.6) | 32(7.9) |
Depression | long-term benzodiazepines use | 41(68.3) | 287(71.2) |
Depression | methyldopa | 1(1.6) | 5 (1.2) |
Concomitant use ≥3 CNS-active drugsb | tricyclic antidepressant + SSRI + benzodiazepine + antipsychotic | 1 (1.6) | 3 (0.7) |
tricyclic antidepressant + SSRI + antipsychotic | 2(3.3) | 4 (1.0) | |
antidepressant + benzodiazepine + antipsychotic | 10 (16.6) | 64 (15.9) | |
antidepressant + benzodiazepine + two antipsychotics | 1 (1.6) | 8 (1.9) |