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Table 1 Baseline clinical characteristics of study participants

From: Value of soluble Urokinase plasminogen activator receptor over age as a biomarker of impaired myocardial relaxation

   Impaired myocardial function (n = 74) Preserved myocardial function (n = 46) Total (n = 120) P-value
Age (years)   73.3 ± 4.0 66.5 ± 13.4 70.3 ± 9.4 0.0001
suPAR   3.9 ± 2.2 3.0 ± 1.4 3.5 ± 2.0 0.015
Female gender   29 (39.2%) 16 (34.8%) 45 (37.5%) 0.63
Body mass index (kg/m2)   23.7 (2.9) 23.3 (3.4) 23.5 (3.1) 0.45
Ever smoker   20 (27.0%) 7 (15.2%) 27 (22.5%) 0.13
Hypertension   41 (55.4%) 24 (52.2%) 65 (54.2%) 0.73
Dyslipidemia   41 (55.4%) 22 (47.8%) 63 (52.5%) 0.42
Diabetes mellitus   20 (27.0%) 5 (10.9%) 25 (20.8%) 0.034
Systolic blood pressure   155.4 (39.3) 145.0 (13.5) 151.4 (39.3) 0.088
Diastolic blood pressure   75.9 (10.3) 76.0 (12.2) 75.9 (10.3) 0.96
Pulse <69 25 (33.8%) 22 (47.8%) 47 (39.2%) 0.13
≥69 49 (66.2%) 24 (52.2%) 73 (60.8%)  
Interventricular septum thickness at end diastole (IVSd) (cm)   0.9 ± 0.2 0.8 ± 0.1 0.8 ± 0.2 0.012
Interventricular septum thickness at end systole (IVSs) (cm)   1.3 ± 0.3 1.2 ± 0.3 1.3 ± 0.3 0.35
Left ventricular internal diameter end diastole (LVIDd) (cm)   4.5 ± 0.5 4.6 ± 0.5 4.5 ± 0.5 0.14
Left ventricular internal diameter end systole (LVIDs) (cm)   2.5 ± 0.4 2.6 ± 0.4 2.5 ± 0.4 0.027
Left ventricular posterior wall end diastole (LVPWd) (cm)   0.8 ± 0.1 0.7 ± 0.1 0.8 ± 0.1 0.074
Left ventricular posterior wall end systole (LVPWs)(cm)   1.4 ± 0.2 1.4 ± 0.2 1.4 ± 0.2 0.62
Left ventricular outflow tract (LVOT) (cm)   2.1 ± 0.1 2.0 ± 0.2 2.1 ± 0.1 0.49
Aortic diameter (Ao) (cm)   3.2 ± 0.4 3.0 ± 0.5 3.1 ± 0.5 0.058
Left atrium (LA) (cm)   3.7 ± 0.5 3.6 ± 0.6 3.7 ± 0.6 0.17
Left ventricular ejection fraction (LVEF) (%)   75.3 ± 6.7 72.7 ± 7.0 74.3 ± 6.9 0.047
Left ventricular fractional shortening (LV FS) (%)   44.3 ± 6.0 42.5 ± 6.3 43.6 ± 6.2 0.13
Left ventricular mass (LVM) (grams)   132.5 ± 41.2 127.6 ± 33.1 130.6 ± 38.2 0.51
Left ventricular mass index (LVMI) (grams/m2)   82.0 ± 23.3 78.5 ± 19.2 80.8 ± 21.9 0.43
Left atrial volume (LAV) (ml)   38.0 ± 13.5 36.7 ± 13.6 37.5 ± 13.5 0.62
Left atrial volume index (LAVI) (ml/m2)   23.6 ± 7.9 22.3 ± 8.0 23.1 ± 7.9 0.42
Peak velocity flow in early diastole E (MV E Peak) (m/s)   0.6 ± 0.1 0.7 ± 0.2 0.7 ± 0.2 0.0001
Peak velocity flow in late diastole by atrial contraction A (MV A Peak) (m/s)   0.8 ± 0.2 0.7 ± 0.2 0.8 ± 0.2 0.0014
Ratio of MV E peak/MV A peak (E/A Ratio)   0.8 ± 0.2 1.1 ± 0.4 0.9 ± 0.3 <0.0001
Deceleration time (DT) (m/s)   218.0 ± 39.0 198.0 ± 37.1 210.3 ± 39.4 0.0064
Pulmonary artery systolic pressure (PASP) (mmHg)   26.9 ± 6.1 27.0 ± 6.7 27.0 ± 6.3 0.94
Pulmonary vein systolic velocity (PV-S) (cm/s)   59.2 ± 11.7 59.1 ± 14.7 59.2 ± 11.7 0.96
Pulmonary vein diastolic velocity (PV-D) (cm/s)   46.8 ± 15.0 51.1 ± 14.1 48.5 ± 14.7 0.13
Pulmonary vein flow at atrial contraction (PV-Ar) (ms)   92.8 ± 17.6 95.1 ± 23.4 93.7 ± 20.0 0.55
Mitral inflow duration at atrial contraction (MV A duration) (ms)   115.8 ± 15.6 113.8 ± 17.2 115.0 ± 16.2 0.51
Peak systolic septal mitral annular velocity (Septal S′) (m/s)   0.08 ± 0.01 0.08 ± 0.01 0.08 ± 0.01 0.72
Peak early diastolic septal mitral annular velocity (Septal E’) (m/s)   0.06 ± 0.02 0.09 ± 0.02 0.07 ± 0.02 <0.0001
Septal mitral annular velocity during atrial contraction (Septal A’) (m/s)   0.1 ± 0.02 0.1 ± 0.02 0.1 ± 0.02 0.69
Ratio of MV E peak/Septal E’   10.1 ± 2.7 9.4 ± 4.4 9.8 ± 3.5 0.28
  1. Continuous data are shown as mean ± SD