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Table 1 Characteristics of the patients with Parkinson’s disease with or without depression or anxiety

From: Prevalence and risk factors for depression and anxiety in Chinese patients with Parkinson disease

 

Total patients (N = 403)

Patients with depression (N = 45)

Patients without depression (N = 358)

P value

Patients with anxiety (N = 104)

Patients without anxiety (N = 299)

P value

Age, years‡

62.6

65.2

62.2

0.097

65.4

61.6

0.002

Men (%)*

55.4

48.8

56.1

0.362

51.5

56.7

0.355

Currently having no partner (%)*

5.3

14.3

5.2

0.096

9.4

5.1

0.485

Schooling year <9(%)*

18.0

29.5

16.6

0.035

24.3

15.9

0.056

Regular exposure (%)*

23.7

23.0

29.3

0.374

28.0

22.2

0.240

Vascular disease (%)*

39.8

47.7

38.7

0.248

43.7

38.3

0.336

Autoimmune disease (%)*

4.5

9.1

4.0

0.247

4.9

4.4

0.856

Stroke (%)*

3.5

2.3

3.7

0.635

7.8

2.0

0.016

tumor (%)*

1.5

4.5

1.1

0.0080

1.0

1.7

0.601

peptic ulcer (%)*

3.5

6.8

3.1

0.208

8.7

1.7

0.002

Having smoking (%)*

18.1

25.0

17.3

0.210

19.4

17.7

0.695

Having drinking (%)*

13.1

15.9

12.7

0.558

12.6

13.3

0.868

Exercise (%)*

53.0

39.5

54.7

0.060

44.1

56.2

0.036

Tea (%)*

22.6

12.2

23.9

0.092

14.0

25.6

0.017

Coffee (%)*

8.5

4.9

8.9

0.562

8.0

8.7

0.841

Age at onset‡

57.1

57.8

57.0

0.758

57.9

56.8

0.358

Duration‡

5.5

7.5

5.3

0.005*

7.5

4.9

< 0.001

H-Y stage‡

1.9

2.5

1.8

< 0.001

2.3

1.8

< 0.001

Family history‡

16.5

12.2

17.0

0.429

11.9

18.1

0.145

MDS-UPDRS II‡

12.1

19.0

11.2

< 0.001

17.4

10.2

< 0.001

MDS-UPDRS III‡

27.9

38.1

26.6

0.001

37.2

24.6

< 0.001

Dyskinesia (%)*

5.5

13.3

4.5

0.034

10.6

3.7

0.008

Fluctuation (%)*

19.6

31.1

18.2

0.039

32.7

15.1

< 0.001

Fast progression (%)*

50%

42.2

51.5

0.238

48.1

51.4

0.566

FOG (%)*

15.9

33.3

13.7

0.001*

34.6

9.4

< 0.001

MMSE‡

26.6

25.4

26.8

0.011

25.3

27.1

< 0.001

PDSS‡

115.7

94.4

118.4

< 0.001

100.7

120.9

< 0.001

HARS/HAMD‡

9.5/7.1

20.4

8.0

< 0.001

12.6

5.1

< 0.001

BPI‡

13.0

25.4

11.4

< 0.001

21.4

10.0

< 0.001

SS-16‡

7.1

6.2

7.2

0.074

6.4

7.4

0.015

RBD‡

17.8

23.5

17.0

0.019

24.0

15.7

< 0.001

SCOPA-AUT‡

12.9

22.4

11.6

< 0.001

21.2

10.0

< 0.001

FSS‡

32.2

44.0

30.6

< 0.001

40.1

29.3

< 0.001

ESS‡

7.3

8.7

7.1

0.075

9.1

6.7

0.001

SN echogenic areas‡

11.3

11.5

11.2

0.831

11.8

10.9

0.645

  1. *chi square test. ‡ Non-parametric statistics (Mann-Whitney test). H-Y stage: modified Hoehn and Yahr staging; MDS-UPDRS: Movement Disorder Society-sponsored revision of the Unified Parkinson’s Disease Rating Scale; FOG: freezing of gait; MMSE: mini-mental state examination; PDSS: the Parkinson’s disease sleep scale; HAMD: 17-item Hamilton Depression Scale; HARS: item Hamilton Anxiety; RBD-HK: the RBD Questionnaire-Hong Kong; SCOPA-AUT: the scale for outcomes in PD for autonomic symptoms; ESS: Epworth Sleepiness Scale; FSS: The Fatigue Severity Scale; BPI: Brief Pain Inventory SN: substantia nigra
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BMC Geriatrics

ISSN: 1471-2318

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