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Table 4 Underlying causes of death among individuals with Down syndrome (n = 513)

From: Mortality patterns and risk among older men and women with intellectual disability: a Swedish national retrospective cohort study

Causes of death Number of deaths
n (%)
Cause-Specific Mortality Rate (per 1000 people)
Ch. X – Diseases of the respiratory system, J00-J99 282 (37.1) 3187
Ch. IX – Diseases of the circulatory system, I00-I99 197 (25.9) 2227
Ch. V – Mental and behavioural disorders, F00-F99 81 (10.7) 916
Ch. VI – Diseases of the nervous system, G00-G99 59 (7.8) 669
Ch. I – Certain infectious and parasitic diseases, A00-B99 33 (4.3) 373
Ch. XVIII – Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified, R00-R99 28 (3.7) 317
Ch. XI – Diseases of the digestive system, K00-K93 16 (2.1) 181
Ch. II – Neoplasms, C00-D48 15 (2) 170
Ch. IV – Endocrine, nutritional and metabolic diseases, E00-E90 14 (1.8) 158
Ch. XIV – Diseases of the genitourinary system, N00-N99 10 (1.3) 113
Ch. XVII – Congenital malformations, deformations and chromosomal abnormalities, Q00-Q99 9 (1.2) 102
Ch. XX – External causes of morbidity and mortality, V01-Y98 8 (1.1) 90
Ch. III – Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism, D50-D89 3 (0.4) 34
Ch. XIX – Injury, poisoning and certain other consequences of external causes, S00-T98 3 (0.4) 34
Ch. XIII – Diseases of the musculoskeletal system and connective tissue, M00-M99 2 (0.3) 23
Ch. XII – Diseases of the skin and subcutaneous tissue, L00-L99 0 (0) NA
Ch. XVI - Certain conditions originating in the perinatal period, P00-P96 0 (0) NA
  1. The total follow-up period for individuals with Down syndrome was 8848 person-years