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Table 4 Underlying causes of death among individuals with Down syndrome (n = 513)

From: Mortality patterns and risk among older men and women with intellectual disability: a Swedish national retrospective cohort study

Causes of death

Number of deaths

n (%)

Cause-Specific Mortality Rate (per 1000 people)

Ch. X – Diseases of the respiratory system, J00-J99

282 (37.1)

3187

Ch. IX – Diseases of the circulatory system, I00-I99

197 (25.9)

2227

Ch. V – Mental and behavioural disorders, F00-F99

81 (10.7)

916

Ch. VI – Diseases of the nervous system, G00-G99

59 (7.8)

669

Ch. I – Certain infectious and parasitic diseases, A00-B99

33 (4.3)

373

Ch. XVIII – Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified, R00-R99

28 (3.7)

317

Ch. XI – Diseases of the digestive system, K00-K93

16 (2.1)

181

Ch. II – Neoplasms, C00-D48

15 (2)

170

Ch. IV – Endocrine, nutritional and metabolic diseases, E00-E90

14 (1.8)

158

Ch. XIV – Diseases of the genitourinary system, N00-N99

10 (1.3)

113

Ch. XVII – Congenital malformations, deformations and chromosomal abnormalities, Q00-Q99

9 (1.2)

102

Ch. XX – External causes of morbidity and mortality, V01-Y98

8 (1.1)

90

Ch. III – Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism, D50-D89

3 (0.4)

34

Ch. XIX – Injury, poisoning and certain other consequences of external causes, S00-T98

3 (0.4)

34

Ch. XIII – Diseases of the musculoskeletal system and connective tissue, M00-M99

2 (0.3)

23

Ch. XII – Diseases of the skin and subcutaneous tissue, L00-L99

0 (0)

NA

Ch. XVI - Certain conditions originating in the perinatal period, P00-P96

0 (0)

NA

  1. The total follow-up period for individuals with Down syndrome was 8848 person-years