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Table 2 Actual HRQOL and subjective expectations for the future

From: Subjective health expectations of patients with age-related macular degeneration treated with antiVEGF drugs

  N (percent) Current EQ-5D score EQ VAS VF-14 Happiness (0–10) TTO Statistical remaining life years** Expected remaining life years Expected EQ-5D scores for future ages
70 80 90
Response rate, N (%)   122 (100) 122 (100) 122 (100) 122 (100) 107 (88) 122 (100) 108 (89) 33 (27) 66 (54) 69 (57)
Total sample 122 0.66 (0.33) 59 (16) 53 (28) 6.3 (2.2) 0.72 (0.30) 10.2 (4.8) 10.4 (6.6) 0.60 (0.41) 0.40 (0.51) 0.24 (0.53)
Gender
 Female 76 (62) 0.56 (0.35) 57 (16)* 50 (26) 6.1 (2.3) 0.68 (0.30) 10.5 (5.4) 9.9 (6.0) 0.57 (0.40) 0.29 (0.56)* 0.08 (0.54)*
 Male 46 (38) 0.81 (0.24) 61 (17)* 58 (31) 6.5 (2.2) 0.79 (0.28) 9.6 (3.4) 11.3 (7.4) 0.65 (0.43) 0.54 (0.41)* 0.51 (0.39)*
AREDS
 One eye in AREDS 4 38 (31) 0.72 (0.28) 61 (18) 57 (33) 6.3 (2.0) 0.83 (0.25)* 10.3 (5.2) 11.3 (7.4) 0.51 (0.55) 0.41 (0.44) 0.24 (0.48)
 Both eyes in AREDS 4 84 (69) 0.63 (0.35) 58 (16) 51 (25) 6.2 (2.3) 0.68 (0.31)* 10.1 (4.6) 10.1 (6.2) 0.64 (0.31) 0.39 (0.56) 0.23 (0.53)
ETDRS change > 15
 No change 97 (81) 0.65 (0.33) 58 (16) 53 (27) 6.4 (2.2) 0.73 (0.30) 9.9 (4.8) 10.5 (6.6) 0.60 (0.42) 0.40 (0.50) 0.24 (0.53)
 Deterioration 23 (19) 0.71 (0.35) 58 (22) 48 (48) 5.7 (2.0) 0.60 (0.32) 11.3 (5.0) 9.6 (6.8) 0.62 (0.15) 0.39 (0.60) 0.20 (0.66)
Expected survivors N (%) 29 (97) 33 (54) 23 (39)
 Yes***: expected age > future age 0.57 (0.40) 0.58 (0.37) 0.40 (0.47)
 No: expected age < future age   0.07 (0) 0.17 (0.59) 0.11 (0.57)
Hospitalization in the last 12 months due to AMD
 No 96 (79) 0.65 (0.33) 57 (16) 55 (26) 6.4 (2.2) 0.70 (0.29) 10.2 (4.7) 10.2 (5.9) 0.63 (0.33) 0.44 (0.52) 0.32 (0.51)*
 Yes 26 (21) 0.67 (0.35) 63 (19) 47 (33) 5.9 (2.5) 0.79 (0.33) 9.9 (5.1) 11.5 (8.8) 0.51 (0.64) 0.27 (0.48) 0.04 (0.54)*
Use of home help in the last month (informal care)
 No 87 (71) 0.76 (0.27)* 61 (16)* 59 (28)* 6.5 (2.1)* 0.76 (0.28)* 10.4 (4.5) 10.9 (7.0) 0.69 (0.31)* 0.47 (0.48)* 0.35 (0.50)*
 Yes 35 (29) 0.41 (0.36)* 53 (16)* 39 (23)* 5.7 (2.6)* 0.63 (0.32)* 9.5 (5.4) 9.2 (5.1) 0.36 (0.53)* 0.02 (0.54)* −0.03 (0.51)*
Biological treatment
 Received in the past 12 months 93 (76) 0.66 (0.33) 57 (16) 55 (27) 6.5 (2.2) 0.70 (0.29) 9.9 (4.7) 10.5 (6.4) 0.65 (0.42) 0.49 (0.51)* 0.34 (0.52)*
 Eligible 29 (24) 0.65 (0.34) 63(16) 46 (31) 5.7 (2.3) 0.78 (0.32) 10.9 (5.1) 10.1 (7.1) 0.47 (0.37) 0.19 (0.48* 0.01 (0.47)*
  1. *p < 0.05
  2. **Age and gender matched survival estimation based on the national Central Statistic Office’s database
  3. ***Respondents who expected to be alive at 70, 80 and 90 years age