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Table 2 Actual HRQOL and subjective expectations for the future

From: Subjective health expectations of patients with age-related macular degeneration treated with antiVEGF drugs

 

N (percent)

Current EQ-5D score

EQ VAS

VF-14

Happiness (0–10)

TTO

Statistical remaining life years**

Expected remaining life years

Expected EQ-5D scores for future ages

70

80

90

Response rate, N (%)

 

122 (100)

122 (100)

122 (100)

122 (100)

107 (88)

122 (100)

108 (89)

33 (27)

66 (54)

69 (57)

Total sample

122

0.66 (0.33)

59 (16)

53 (28)

6.3 (2.2)

0.72 (0.30)

10.2 (4.8)

10.4 (6.6)

0.60 (0.41)

0.40 (0.51)

0.24 (0.53)

Gender

 Female

76 (62)

0.56 (0.35)

57 (16)*

50 (26)

6.1 (2.3)

0.68 (0.30)

10.5 (5.4)

9.9 (6.0)

0.57 (0.40)

0.29 (0.56)*

0.08 (0.54)*

 Male

46 (38)

0.81 (0.24)

61 (17)*

58 (31)

6.5 (2.2)

0.79 (0.28)

9.6 (3.4)

11.3 (7.4)

0.65 (0.43)

0.54 (0.41)*

0.51 (0.39)*

AREDS

 One eye in AREDS 4

38 (31)

0.72 (0.28)

61 (18)

57 (33)

6.3 (2.0)

0.83 (0.25)*

10.3 (5.2)

11.3 (7.4)

0.51 (0.55)

0.41 (0.44)

0.24 (0.48)

 Both eyes in AREDS 4

84 (69)

0.63 (0.35)

58 (16)

51 (25)

6.2 (2.3)

0.68 (0.31)*

10.1 (4.6)

10.1 (6.2)

0.64 (0.31)

0.39 (0.56)

0.23 (0.53)

ETDRS change > 15

 No change

97 (81)

0.65 (0.33)

58 (16)

53 (27)

6.4 (2.2)

0.73 (0.30)

9.9 (4.8)

10.5 (6.6)

0.60 (0.42)

0.40 (0.50)

0.24 (0.53)

 Deterioration

23 (19)

0.71 (0.35)

58 (22)

48 (48)

5.7 (2.0)

0.60 (0.32)

11.3 (5.0)

9.6 (6.8)

0.62 (0.15)

0.39 (0.60)

0.20 (0.66)

Expected survivors N (%)

–

–

–

–

–

–

–

–

29 (97)

33 (54)

23 (39)

 Yes***: expected age > future age

–

–

–

–

–

–

–

–

0.57 (0.40)

0.58 (0.37)

0.40 (0.47)

 No: expected age < future age

 

–

–

–

–

–

–

–

0.07 (0)

0.17 (0.59)

0.11 (0.57)

Hospitalization in the last 12 months due to AMD

 No

96 (79)

0.65 (0.33)

57 (16)

55 (26)

6.4 (2.2)

0.70 (0.29)

10.2 (4.7)

10.2 (5.9)

0.63 (0.33)

0.44 (0.52)

0.32 (0.51)*

 Yes

26 (21)

0.67 (0.35)

63 (19)

47 (33)

5.9 (2.5)

0.79 (0.33)

9.9 (5.1)

11.5 (8.8)

0.51 (0.64)

0.27 (0.48)

0.04 (0.54)*

Use of home help in the last month (informal care)

 No

87 (71)

0.76 (0.27)*

61 (16)*

59 (28)*

6.5 (2.1)*

0.76 (0.28)*

10.4 (4.5)

10.9 (7.0)

0.69 (0.31)*

0.47 (0.48)*

0.35 (0.50)*

 Yes

35 (29)

0.41 (0.36)*

53 (16)*

39 (23)*

5.7 (2.6)*

0.63 (0.32)*

9.5 (5.4)

9.2 (5.1)

0.36 (0.53)*

0.02 (0.54)*

−0.03 (0.51)*

Biological treatment

 Received in the past 12 months

93 (76)

0.66 (0.33)

57 (16)

55 (27)

6.5 (2.2)

0.70 (0.29)

9.9 (4.7)

10.5 (6.4)

0.65 (0.42)

0.49 (0.51)*

0.34 (0.52)*

 Eligible

29 (24)

0.65 (0.34)

63(16)

46 (31)

5.7 (2.3)

0.78 (0.32)

10.9 (5.1)

10.1 (7.1)

0.47 (0.37)

0.19 (0.48*

0.01 (0.47)*

  1. *p < 0.05
  2. **Age and gender matched survival estimation based on the national Central Statistic Office’s database
  3. ***Respondents who expected to be alive at 70, 80 and 90 years age
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BMC Geriatrics

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