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Table 5 Multiple linear regression - total tau

From: Factors that influence the levels of cerebrospinal fluid biomarkers in memory clinic patients

Variables

Unadjusted standardized beta

P

R square

Adjusted standardized beta

P

Patients with MMSE sum score ≥ 25, N = 134

 Diagnoses (AD/aMCI = 2, others = 1)

0.44

<0.001

0.19

0.36

<0.001

 Age

0.12

0.16

0.007

  

 Sex (1 = women, 2 = men)

−0.17

0.05

0.02

  

 ApoE ε4 genotype (neg = 1, pos = 2)

0.26

0.002

0.06

0.2

0.008

 Amyloid β

−0.36

<0.001

0.12

  

 MMSE

−0.39

<0.001

0.15

−0.31

0.001

 R square

   

0.32

 

Patients with MMSE sum score < 25, N = 119

 Age

0.07

0.46

−0.004

  

 Sex (1 = women, 2 = men)

−0.02

0.87

−0.008

  

 ApoE ε4 genotype (neg = 1, pos = 2)

0.18

0.05

0.03

  

 Amyloid β

−0.25

0.005

0.06

−0.24

0.01

 MMSE

−0.16

0.09

0.02

  

 R square

   

0.07

 
  1. AD/aMCI Alzheimer’s dementia/amnestic mild cognitive impairment
  2. MMSE missing in 4 patients