Table 1 Characteristics of the patients
From: Factors that influence the levels of cerebrospinal fluid biomarkers in memory clinic patients
MCI patients (N = 67) | AD patients (N = 165) | Other dementias (N = 25) | P | |
|---|---|---|---|---|
Patient characteristics | ||||
Age [mean (SD)] | 66.7 (9.3) | 68.7 (7.1) | 67.8 (9.3) | 0.22a |
Women [n (%)] | 34 (50.7) | 87 (52.7) | 8 (32.0) | 0.15b |
Education [mean (SD)] | 12.8 (4.0) | 12.2 (3.4) | 12.3 (3.9) | 0.54a |
ApoE ε4 positive [n (%)] | 40 (59.7) | 118 (71.5) | 13 (52.0) | 0.06b |
Cognition | ||||
MMSE [mean (SD)] | 26.9 (3.0) | 22.7 (4.4) | 24.2 (3.8) | <0.001c |
CDT accepted [n (%)] | 54 (83.1) | 76 (47.5) | 15 (60.0) | <0.001b |
TMT A ≥ −2 SD [n (%)] | 55 (83.3) | 89 (58.0) | 10 (41.7) | <0.001b |
TMT B ≥ −2 SD [n (%)] | 45 (69.2) | 57 (41.0) | 7 (31.8) | <0.001b |
CSF biomarkers | ||||
Aβ [mean (SD)] | 799.1 (315.6) | 583.3 (210.5) | 735.9 (281.7) | <0.001c |
T-Tau [mean (SD)] | 464.7 (260.8) | 717.0 (357.9) | 305.1 (165.4) | <0.001c |
P-tau [mean (SD)] | 63.6 (24.4) | 83.6 (35.0) | 47.3 (16.7) | <0.001c |