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Table 1 Characteristics of the patients

From: Factors that influence the levels of cerebrospinal fluid biomarkers in memory clinic patients

  MCI patients (N = 67) AD patients (N = 165) Other dementias (N = 25) P
Patient characteristics
 Age [mean (SD)] 66.7 (9.3) 68.7 (7.1) 67.8 (9.3) 0.22a
 Women [n (%)] 34 (50.7) 87 (52.7) 8 (32.0) 0.15b
 Education [mean (SD)] 12.8 (4.0) 12.2 (3.4) 12.3 (3.9) 0.54a
 ApoE ε4 positive [n (%)] 40 (59.7) 118 (71.5) 13 (52.0) 0.06b
Cognition
 MMSE [mean (SD)] 26.9 (3.0) 22.7 (4.4) 24.2 (3.8) <0.001c
 CDT accepted [n (%)] 54 (83.1) 76 (47.5) 15 (60.0) <0.001b
 TMT A ≥ −2 SD [n (%)] 55 (83.3) 89 (58.0) 10 (41.7) <0.001b
 TMT B ≥ −2 SD [n (%)] 45 (69.2) 57 (41.0) 7 (31.8) <0.001b
CSF biomarkers
 Aβ [mean (SD)] 799.1 (315.6) 583.3 (210.5) 735.9 (281.7) <0.001c
 T-Tau [mean (SD)] 464.7 (260.8) 717.0 (357.9) 305.1 (165.4) <0.001c
 P-tau [mean (SD)] 63.6 (24.4) 83.6 (35.0) 47.3 (16.7) <0.001c
  1. MCI mild cognitive impairment, AD Alzheimer’s Disease, MMSE Mini Mental State Examination, CDT the Clock Drawing Test, TMT Trail Making Test A and B, Amyloid β, T-tau total tau, P-tau phosho tau
  2. % = valid percent without missing
  3. aone-way ANOVA, bChi square, cKruskal-Wallis test
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